Protein Alignment CG43366 and SERPINA11

DIOPT Version :9

• Sequence 1: NP_610188.2
• Gene: CG43366 / 35519
• FlyBaseID: FBgn0263109
• Length: 2140
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 110/512 - (21%)
• Similarity: 193/512 - (37%)
• Gaps: 160/512 - (31%)

  Fly  1660 PSPESSQGLEASTA--MMDEDLQSFA-RLCNELAFSYWRAITSEKISSARSLVISPFALTSMLSM 1721
            |.|...|..|.:.|  .:...:.:|| ||..|||           ..:..::..||.::::.|::
Human    33 PQPPRHQLSEPAPAYHRITPTITNFALRLYKELA-----------ADAPGNIFFSPVSISTTLAL 86

  Fly  1722 VFLGARGSTSGEMNEILKLDDMVTFNP----HLIFKNITNSVEQAS---DSDIATAAFVREIFSD 1779
            :.|||:.:||..:.|.|..:  :|..|    |..|:::.:::...|   :..:..:.|:.:....
Human    87 LSLGAQANTSALILEGLGFN--LTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKP 149

  Fly  1780 RANGKILPFFKEKTQQLYAGHVEEVNFHVVNDIVR--RRTNLLVKRHTMGKVLE----------- 1831
            |.:      :.:..::||.......||   .|.|.  |:.|..::|.|.|:|::
Human   150 RQH------YLDSIKELYGAFAFSANF---TDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFM 205

  Fly  1832 ----YLRTNSVWVNGPLATISANLFQTDCSHGSTTDRDGEMFFQVHPTVRQRRLVPIPAV----L 1888
                |:...:.|.: |.:.     :||         :..|.||     |.:|..:.:|.:    :
Human   206 VLANYIFFKAKWKH-PFSR-----YQT---------QKQESFF-----VDERTSLQVPMMHQKEM 250

  Fly  1889 YRSGFLAGYEPSLDATVVSFGRVQNTVSTVYVMPGHQSSISPMDNLDRLERSLVETAFSDK--QA 1951
            :|  ||  |:..|..||:......|.:: :.|:|            |..:...||.|...:  :.
Human   251 HR--FL--YDQDLACTVLQIEYRGNALA-LLVLP------------DPGKMKQVEAALQPQTLRK 298

  Fly  1952 W-RRLLTSLMDRPGMEVQLPRFSHRSFVNASLGLQKMGLRGLFKSDFADLRGLTGAGNRDIFLSD 2015
            | :.||.||:|     :.|||||.....|....|.::||..:...: ||..|:||..|:.|
Human   299 WGQLLLPSLLD-----LHLPRFSISGTYNLEDILPQIGLTNILNLE-ADFSGVTGQLNKTI---- 353

  Fly  2016 MIQINTFSTCGEEKISEHHHVEMYPAPPLRKRNKDVDATDDDAFDSSERVVDFGSLVQESALGRG 2080
                        .|:|....|:|                       ||:..:.|     :|.|
Human   354 ------------SKVSHKAMVDM-----------------------SEKGTEAG-----AASG-- 376

  Fly  2081 FYDDLLDPKYLELPLPLRPRQARVPDAPRLRFDKPFLYFVRHNPTGMILFMGR-FNP 2136
                          |..:|........|...|::|||..:....|..:||:|: .||
Human   377 --------------LLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	99/480 (21%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	103/487 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100