DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43366 and Serpina3j

DIOPT Version :9

Sequence 1:	NP_610188.2	Gene:	CG43366 / 35519	FlyBaseID:	FBgn0263109	Length:	2140	Species:	Drosophila melanogaster
Sequence 2:	NP_001094942.1	Gene:	Serpina3j / 238395	MGIID:	2182843	Length:	420	Species:	Mus musculus

Alignment Length:	508	Identity:	114/508 - (22%)
Similarity:	189/508 - (37%)	Gaps:	138/508 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1649 TQSTRPPVKLDPSPESSQGLEASTAMMDEDLQSFARLCNELAFSYWRAITSEKISSARSLVISPF 1713
            |.....||:.|...|:..           |..:.|.:..:.|||.::.:..:  :..::.|.||.
Mouse    25 TLGKHTPVQKDRDHETQL-----------DSLTLASINTDFAFSLYKKLALK--NPHKNFVFSPL 76

  Fly  1714 ALTSMLSMVFLGARGSTSGEMNEILKLDDMVTFNP----HLIFKNITNSVEQASDS-DIATA-AF 1772
            ::|..|:.:.|||:|:|..|:.|.||.:  :|..|    |..|.::...:.|..|. .|:|. :.
Mouse    77 SITIALASLSLGAKGNTLEEILEGLKFN--LTETPEADIHQGFGHLLQRLSQPGDQVQISTGNSM 139

  Fly  1773 VREIFSDRANGKILPFFKEKTQQLYAGHVEEVNFHVVNDIVRRRTNLLVKRHTMGKVLEYL---- 1833
            |.|     .:.:||..||||.:.||...|...:|....: .|:..|..|...|.|.:.|.:
Mouse   140 VVE-----KHLQILAEFKEKARALYHTEVFTADFQQPRE-ARKLLNDYVSNQTQGMIKELVSDLE 198

  Fly  1834 -RTNSVWVNGPLATISANLFQTDCSHGSTTDRDGEMFFQVHPT-----VRQRRLVPIPAVLYRSG 1892
             ||:.|..|..|.....|                 |.|..:.|     :..|| .|:...:.:..
Mouse   199 ERTSMVMTNFALFNGKWN-----------------MTFDPYETFMGTFIEDRR-TPVKVSMMKMK 245

  Fly  1893 FL-AGY--EPSLDATVVSFGRVQNTVSTVYVMPGHQSSISPMDNLDRLERSLVETAFSDKQAWRR 1954
            .| |.|  :..:..|||......|. ..::::|       ....:.::|.||.....   :.||:
Mouse   246 ELRAPYFRDEKMKCTVVELNYKGNG-KAMFILP-------DQGKMKQVEASLQPATL---RGWRK 299

  Fly  1955 LLTSLMDRPGM--EVQLPRFSHRSFVNASLGLQKMGLRGLFKSDFADLRGLTGAGNRDIFLSDMI 2017
            .|     ||.|  |:.||:||..........|.::|::.:|.:. |||.|:  :|.:|:.:|.|.
Mouse   300 SL-----RPRMIDELYLPKFSISKNYRLENILPELGIKEVFSTQ-ADLSGI--SGGKDVRVSRMF 356

  Fly  2018 QINTFSTCGEEKISEHHHVEMYPAPPLRKRNKDVDATDDDAFDSSERVVDFGSLVQESALGRGFY 2082
                            |..    |..:.:...:..||..|.:|                    |.
Mouse   357 ----------------HSA----ALDMTETGTEARATTRDKYD--------------------FL 381

  Fly  2083 DDLLDPKYLELPLPLRPRQARVPDAPRLRFDKPFLYFVRHNPTGMILFMGRFN 2135
            ....:|..:.|                   :.|||:.|.|:.:..|.|||:.|
Mouse   382 STKSNPTVVNL-------------------NTPFLFCVLHSDSENIDFMGKIN 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	107/470 (23%)
Serpina3j	NP_001094942.1	serpinA3_A1AC	37..417	CDD:381019	110/496 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100