Protein Alignment CG43366 and Serpina10

DIOPT Version :10

• Sequence 1: NP_610188.2
• Gene: CG43366 / 35519
• FlyBaseID: FBgn0263109
• Length: 2140
• Species: Drosophila melanogaster
• Sequence 2: NP_659083.2
• Gene: Serpina10 / 217847
• MGIID: 2667725
• Length: 448
• Species: Mus musculus
• Alignment Length: 568
• Identity: 114/568 - (20%)
• Similarity: 200/568 - (35%)
• Gaps: 172/568 - (30%)

  Fly  1606 VLPYNANKADPVQLQVPIHSQSMLNQQRPSQRPPLLINLMASSTQSTRPPVKLDPSPESSQGLEA 1670
            |..:|.:...| :..|.:.||...||               :..:.||    .||..|..:..|.
Mouse    19 VTSFNLSSHSP-EASVHLESQDYENQ---------------TWEEYTR----TDPREEEEEEEEK 63

  Fly  1671 STAMMDED--LQSFARLCNE---LAFSYWRAITSEKISSAR--SLVISPFALTSMLSMVFLGARG 1728
            ... .||:  |::..:|.||   ..|:..|     |||...  :::.|||.|:..:..:.||.:|
Mouse    64 EEG-KDEEYWLRASQQLSNETSSFGFNLLR-----KISMRHDGNVIFSPFGLSVAMVNLMLGTKG 122

  Fly  1729 STSGEMNEILKLDDMVTFNPHL---IFKNITNSVEQASDSDIA--TAAFVREIFSDRANGKILPF 1788
            .|..::...|.|..:....|.:   :||.:..:.....|..::  :.||:.:.|.
Mouse   123 ETKVQIENGLNLQALSQAGPLILPALFKKVKETFSSNRDLGLSQGSFAFIHKDFD---------- 177

  Fly  1789 FKEKTQQLYAGH--VEEVNFHVVNDI-VRRRTNLLVKRHTMGKV---------------LEYLRT 1835
            .||....|...:  :|.|:.:..|.. .|...|..:.:.|.||:               ::|:..
Mouse   178 IKETYFNLSKKYFDIEYVSINFQNSSQARGLINHCIVKETEGKIPKLFDEINPETKLILVDYVLF 242

  Fly  1836 NSVWVNGPLATISANLFQTDCSHGSTTDRDGEMFFQVHPTVRQRRLVPIPAVLYRSG-FLAGYEP 1899
            ...|    |.....:..:.|..|                 :.:.|.:.:| ::||.| |.:.::.
Mouse   243 KGKW----LTPFDPSFTEADTFH-----------------LDKYRAIKVP-MMYREGNFTSTFDK 285

  Fly  1900 SLDATVVSFGRVQNTVSTVYVM--PGHQSSISPMDNLDRLERSLVETAFSDKQAWRRLLTSLMDR 1962
            .....::......|....|.:|  .|...::.     |.|...||||       |   |.::..|
Mouse   286 KFRCHILKLPYQGNATMLVVLMEKTGDYLALE-----DYLTVDLVET-------W---LQNMKTR 335

  Fly  1963 PGMEVQLPRFSHRSFVNASLGLQKMGLRGLFKSDFADLRGLTGAGNRDIFLSDMIQINTFSTCGE 2027
            . |||..|:|...........|::||:|.|| |..|||..|: |..|::.:|.::|.:..
Mouse   336 K-MEVFFPKFKLNQRYEMHELLKQMGIRRLF-STSADLSELS-AMARNLQVSRVLQQSVL----- 392

  Fly  2028 EKISEHHHVEMYPAPPLRKRNKDVDATDDDAFDSSERVVDFGSLVQESALGRGFYDDLLDPKYLE 2092
                                  :||....:|..        |:|                .:.:.
Mouse   393 ----------------------EVDERGTEAVS--------GTL----------------SEIIA 411

  Fly  2093 LPLPLRPRQARVPDAPRLRFDKPFLYFVRHNPTGMILFMGR-FNPRLL 2139
            ..:|           |.::.::||.:.:....:.|:||:|| .||.:|
Mouse   412 YSMP-----------PAIKVNRPFHFIIYEEMSRMLLFLGRVVNPTVL 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	MDN1	956..>1505	CDD:444083
		Serpin	1687..2136	CDD:459662	93/480 (19%)
Serpina10	NP_659083.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..70		12/56 (21%)
		serpinA10_PZI	71..446	CDD:381011	96/491 (20%)
		Heparin-binding. /evidence=ECO:0000250	140..157		3/16 (19%)