Protein Alignment CG43366 and Serpina12

DIOPT Version :9

• Sequence 1: NP_610188.2
• Gene: CG43366 / 35519
• FlyBaseID: FBgn0263109
• Length: 2140
• Species: Drosophila melanogaster
• Sequence 2: NP_620180.2
• Gene: Serpina12 / 191570
• RGDID: 708485
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 95/477 - (19%)
• Similarity: 179/477 - (37%)
• Gaps: 125/477 - (26%)

  Fly  1677 EDLQSFARLCNELAFSYWRAITSEKISSARSLVISPFALTSMLSMVFLGARGSTSGEMNEILKLD 1741
            :|.:...|...|..|...:.:.|.  |...::.:||.::::..||:.|||:.||..|:.|.....
  Rat    43 KDARELTRHNMEFGFKLLQRLASN--SRQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFK 105

  Fly  1742 DMVTFNPHLIFKNITNSVEQASDS---DIATAAFVREIFSDRANGKILPFFKEKTQQLYAGHVEE 1803
            :|...:.|:.|..:...:.:.:..   .|..|.|:.:....:..      |.:..:.||...:..
  Rat   106 EMSDRDMHMGFHYLLQKLNRETQDVKMSIGNALFMDQRLRPQQR------FLKLAKNLYDADMIL 164

  Fly  1804 VNFH-------VVNDIVRRRTN----LLVKRHTMGKVLEYLRTNSVWVNGPLATISANLFQTDCS 1857
            .||.       .:|..:.|:|:    .:||....|.|:  |.||.::..|        .:|.:..
  Rat   165 TNFQDLENTQKNINKYISRKTHNRIENMVKNIDPGTVM--LLTNYIYFQG--------RWQYEFD 219

  Fly  1858 HGSTTDRDGEMFFQVHPTVRQRRLVPIPAVLYRSGFLAGYEPSLDATVVSFGRVQNTVSTVYVMP 1922
            ...|.:.|   ||     :.:.:.|.:|.:..|..:...|:..|..|::.....:|..:| :|:|
  Rat   220 PKQTKEED---FF-----IEEGKTVKVPMMFQRGMYDMAYDSQLSCTILEMPYRRNITAT-FVLP 275

  Fly  1923 GHQSSISPMDNLDRLERSLVETAFSDKQAWRRLLTSLMDRPGMEVQLPRFSHRSFVNASLGLQKM 1987
                   ....|..||:.|....|:   .|:    ||:.:..::|.:||....:..|....|.::
  Rat   276 -------DSGKLRLLEQGLQADIFA---KWK----SLLSKRVVDVWVPRLHISATYNMKKVLSRL 326

  Fly  1988 GLRGLFKSDFADLRGLTGAGNRDIFLSDMIQINTFSTCGEEKISEHHHVEMYPAPPLRKRNKDVD 2052
            |:..:|: :..||                           .:||.|..:::
  Rat   327 GISKIFE-EHGDL---------------------------TRISSHRSLKV-------------- 349

  Fly  2053 ATDDDAFDSSE-RVVDFGSLVQESALGRGFYDDLLDPKYLELPLPLR-PRQARVPDAPRLRFDKP 2115
               .:|...:| |:.:.|:   |.|.|.|           ...||:. ||        |::.:.|
  Rat   350 ---GEAVHKAELRMNEKGT---EGAAGSG-----------AQTLPMETPR--------RMKLNAP 389

  Fly  2116 FLYFVRHNPTGMILFMGR-FNP 2136
            ||..:..|....::|:.| :||
  Rat   390 FLMMIYENLMPSMIFLARIYNP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	91/465 (20%)
Serpina12	NP_620180.2	alpha-1-antitrypsin_like	51..408	CDD:239011	90/464 (19%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		7/31 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100