DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43366 and Serpinf2

DIOPT Version :9

Sequence 1:	NP_610188.2	Gene:	CG43366 / 35519	FlyBaseID:	FBgn0263109	Length:	2140	Species:	Drosophila melanogaster
Sequence 2:	NP_032904.1	Gene:	Serpinf2 / 18816	MGIID:	107173	Length:	491	Species:	Mus musculus

Alignment Length:	547	Identity:	111/547 - (20%)
Similarity:	201/547 - (36%)	Gaps:	159/547 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1621 VPIHSQSMLNQQRPSQRP-PLLINL----MASSTQSTRPP--VKLDPSPESSQGLEASTAMMDED 1678
            |.:..|..:::|...:.| |.|..|    ........|.|  .|..|:.|.::.|..:......|
Mouse    28 VDLPGQQPVSEQAQQKLPLPALFKLDNQDFGDHATLKRSPGHCKSVPTAEETRRLAQAMMAFTTD 92

  Fly  1679 LQSFARLCNELAFSYWRAITSEKISSARSLVISPFALTSMLSMVFLGARGSTSGEMNEILKLDDM 1743
            |.|..                .:.|::.:||:||.::...||.:.|||:..|...::.:|.::..
Mouse    93 LFSLV----------------AQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHMNTG 141

  Fly  1744 VTFNPHLI---FKNITNSVEQASDSDIATAAFVREIFSDRANGKILPFFKEKTQQLYAGHVEEVN 1805
            ... |||:   ::|:.....:     :|...::::.|      .|...|.|::::|:.....::.
Mouse   142 SCL-PHLLSHFYQNLGPGTIR-----LAARIYLQKGF------PIKDDFLEQSERLFGAKPVKLT 194

  Fly  1806 FHVVNDIVRRRTNLLVKRHTMGKVLEYLRTNSVWVNGPLATISANLFQTDCSHG--------STT 1862
            .....|:.  ..|..||..|.||:.::|  :.:..:..|..::|..|     ||        |.|
Mouse   195 GKQEEDLA--NINQWVKEATEGKIEDFL--SELPDSTVLLLLNAIHF-----HGFWRTKFDPSLT 250

  Fly  1863 DRDGEMFFQVHPTVRQRRLVPIP---AVLYRSGFLAGYEPSLDATVVSFGRVQNTVSTVYVMPGH 1924
            .:|   ||.:.    :|..|.:.   ||.|...:....:|.:......|   :|.:|.|.|||.:
Mouse   251 QKD---FFHLD----ERFTVSVDMMHAVSYPLRWFLLEQPEIQVAHFPF---KNNMSFVVVMPTY 305

  Fly  1925 -QSSISP-MDNLDRLERSLVETAFSDKQAWRRLL-TSLMDRPGMEVQLPRFSHRSFVNASLGLQK 1986
             :.::|. :.||                .|..|. .||.:|| .:|.||:...:..::....|.:
Mouse   306 FEWNVSEVLANL----------------TWDTLYHPSLQERP-TKVWLPKLHLQQQLDLVATLSQ 353

  Fly  1987 MGLRGLFKSDFADLRGLTGAGNRDIFLSDMIQINTFSTCGEEKISEHHHVEMYPAPPLRKRNKDV 2051
            :||:.||:.  .||||::   .:::.:|                |..|...|
Mouse   354 LGLQELFQG--PDLRGIS---EQNLVVS----------------SVQHQSTM------------- 384

  Fly  2052 DATDDDAFDSSERVVDFGSLVQESALGRGFYDDLLDPKYLELPLPLRPRQARVPDAPRLRFDKPF 2116
                    :.||..|: .:.....|:.|                         ........::||
Mouse   385 --------ELSEAGVE-AAAATSVAMNR-------------------------MSLSSFTVNRPF 415

  Fly  2117 LYFVRHNPTGMILFMGRF---NPRLLP 2140
            |:|:..:..|:.||:|..   ||..||
Mouse   416 LFFIMEDTIGVPLFVGSVRNPNPSALP 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	91/468 (19%)
Serpinf2	NP_032904.1	alpha2AP	82..433	CDD:239008	95/482 (20%)
Serpinf2	NP_032904.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..491		2/4 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100