Protein Alignment CG43366 and Serpind1

DIOPT Version :9

• Sequence 1: NP_610188.2
• Gene: CG43366 / 35519
• FlyBaseID: FBgn0263109
• Length: 2140
• Species: Drosophila melanogaster
• Sequence 2: NP_001317976.1
• Gene: Serpind1 / 15160
• MGIID: 96051
• Length: 478
• Species: Mus musculus
• Alignment Length: 496
• Identity: 97/496 - (19%)
• Similarity: 184/496 - (37%)
• Gaps: 128/496 - (25%)

  Fly  1663 ESSQGLEASTAMMDEDLQSFARLCNELAFSYWRAITSEKISSARSLVISPFALTSMLSMVFLGAR 1727
            |||.|...........:|....|..:.||:.:| :..::.:::.:|.|:|..:::.:.|:.||.|
Mouse    86 ESSAGNILQLFQGKSRIQRLNILNAKFAFNLYR-VLKDQATTSDNLFIAPVGISTAMGMISLGLR 149

  Fly  1728 GSTSGEMNEILKLDDMVTFNP-------HLIFKNITNSVEQAS---DSDIATAAFVREIFSDRAN 1782
            |.|..|::.:|...|.|..:.       |.:|:.:|:.:.:.:   ........::::.|..|.:
Mouse   150 GETHEEVHSVLHFRDFVNASSKYEVTTIHNLFRKLTHRLFRRNFGYTLRSVNGLYIQKQFPIRED 214

  Fly  1783 GKILPFFKEKTQQLYAGHVEEVNF------HVVNDIVRRRTNLLVKR--HTMGKVLEYLRTNSVW 1839
                  ||...::.|....:|.||      ...|:.:.:.|..|:|.  ..:....:.|..|.::
Mouse   215 ------FKAAMREFYFAEAQEANFPDPAFISKANNHILKLTKGLIKEALENIDPATQMLILNCIY 273

  Fly  1840 VNGPLATISANLFQTDCSHGSTTDRDGEMFFQVHPTVRQRRLVPIPAVLYRSGFLAGYEPSLDAT 1904
            ..|..    .|.|..:.:|...        |:::    :|.:|.:..:..:..|||..:..||..
Mouse   274 FKGTW----VNKFPVEMTHNHN--------FRLN----EREVVKVSMMQTKGNFLAANDQELDCD 322

  Fly  1905 VVSFGRVQNTVSTVYVMPGHQSSISPMDNLD-RLERSLVETAFSDKQAWRRLLTSLMDRPGMEVQ 1968
            ::....| ..:|.:.|:|   ..:|.|..|: :|...:||       .|::.:|:..    .||.
Mouse   323 ILQLEYV-GGISMLIVVP---RKLSGMKTLEAQLTPQVVE-------RWQKSMTNRT----REVL 372

  Fly  1969 LPRFSHRSFVNASLGLQKMGLRGLFKSDFADLRGLTGAGNRDIFLSDMIQINTFSTCGEEKISEH 2033
            ||:|......|....|:.||:..||..:          ||........|.|:.|
Mouse   373 LPKFKLEKNYNLVEVLKSMGITKLFNKN----------GNMSGISDQRIAIDLF----------- 416

  Fly  2034 HHVEMYPAPPLRKRNKDVDATDDDAFDSSERVVDFGSLVQESALGRGFYDDLLDPKYLELPLPLR 2098
                        |....:...::....::...|.|
Mouse   417 ------------KHQSTITVNEEGTQAAAVTTVGF------------------------------ 439

  Fly  2099 PRQARVPDAPRLRF--DKPFLYFVRHNPTGMILFMGRF-NP 2136
                 :|.:.::||  |:|||:.|..:.|..:||||:. ||
Mouse   440 -----MPLSTQVRFTVDRPFLFLVYEHRTSCLLFMGKVTNP 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	89/470 (19%)
Serpind1	NP_001317976.1	HCII	43..476	CDD:239002	97/496 (20%)
		2 X 11 AA approximate repeats, Asp/Glu-rich (acidic) (hirudin-like)	54..78
		Glycosaminoglycan-binding site. /evidence=ECO:0000250	171..191		3/19 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100