DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZnT41F and MTPA2

DIOPT Version :9

Sequence 1:	NP_610185.1	Gene:	ZnT41F / 35513	FlyBaseID:	FBgn0025693	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_191440.2	Gene:	MTPA2 / 825050	AraportID:	AT3G58810	Length:	432	Species:	Arabidopsis thaliana

Alignment Length:	410	Identity:	135/410 - (32%)
Similarity:	215/410 - (52%)	Gaps:	54/410 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 CGDSARNQSSETEFDMQRECCNHQP-GFR-ANSKSKSAQE---AKYKIMLAVALCCVFMIIEFLG 150
            ||:.:   |.||.....::.|...| ||. |.:.|..|||   :..|:::||.||.:|:::|.:|
plant    69 CGEVS---SGETSLVGIKKTCGEAPCGFSDAKTSSIEAQERAASMRKLLIAVLLCAIFIVVEVVG 130

  Fly   151 GYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWFVTT 215
            |..|.||||:||||||.||..:|.|.|.::|..|...:.:.|:|:.|.|::|||.||..||.:..
plant   131 GIKANSLAILTDAAHLLSDVAAFAISLFSLWASGWKANPQQSYGFFRIEILGALVSIQMIWLLAG 195

  Fly   216 LLVVVAIERIFSQDFELNADMMMLISGIGIVINIVMMFVL-HGSWFVNGNGHGHSHSHSHSHSHS 279
            :||..||.|:.:...|:...:|..:|.:|:::||.|..:| |.    :|:||||||.:.|.|||.
plant   196 ILVYEAIVRLNNGSGEVEGSLMFAVSAVGLLVNIAMAILLGHD----HGHGHGHSHDNGHGHSHD 256

  Fly   280 HGNGHEPNDSLSQTRSNSNFLTTIGSQSASTADEEDSIRKEINSNEHKIVITNGKKPTLTGTSNM 344
            ||:|                       .|:|....||...|...::   |:...||
plant   257 HGHG-----------------------IAATEHHHDSGHDESQLSD---VLIEQKK--------- 286

  Fly   345 ELAHEDKNLNLRAAMIHVIGDLVQSIGVFLAAVLIKVCPGAKYADPLCTLIFSIIVIMTTLRLFR 409
                 .:|:|::.|.:||:||.:||:||.:...:|...|..|..|.:|||:||:||:.||:.:.|
plant   287 -----QRNVNIQGAYLHVLGDSIQSVGVMIGGAIIWYKPEWKILDLICTLVFSVIVLGTTIGMLR 346

  Fly   410 ESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTSQQRVLMVHLVTDSRADGNEVLQA 474
            ..|.:::.:.|:.::...|...:..||.|.::|.|::|..|..:.:|..|:.....|:.:.||..
plant   347 NILEVLMESTPREIDPTMLEKGVCEIEEVVAVHELHIWAITVGKLLLACHVKIRPEAEADMVLDK 411

  Fly   475 ATALVSSPRYNIKHSTIQLE 494
            ....:.. .:||.|.|||:|
plant   412 IIDYIKR-EHNISHVTIQIE 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZnT41F	NP_610185.1	CDF	142..495	CDD:273544	116/354 (33%)
ZnT41F	NP_610185.1	Cation_efflux	142..416	CDD:279834	95/274 (35%)
MTPA2	NP_191440.2	CDF	122..430	CDD:273544	115/352 (33%)
MTPA2	NP_191440.2	Cation_efflux	122..353	CDD:279834	95/274 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53838
OrthoDB	1	1.010	-	-		D973492at2759
OrthoFinder	1	1.000	-	-		FOG0000470
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11562
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.890