Protein Alignment ZnT41F and SLC30A10

DIOPT Version :9

• Sequence 1: NP_610185.1
• Gene: ZnT41F / 35513
• FlyBaseID: FBgn0025693
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_061183.2
• Gene: SLC30A10 / 55532
• HGNCID: 25355
• Length: 485
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 94/404 - (23%)
• Similarity: 181/404 - (44%)
• Gaps: 71/404 - (17%)

  Fly   132 KIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPP-DERMSFGY 195
            :::..:.|...|.:.|.:.||:..|:|:::|:.::.||.||..:||.|.:|..||. ....::||
Human    10 RLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLSAGYIARRPTRGFSATYGY 74

  Fly   196 KRFEVIGALASILGIWFVTTLLVVVAIERI--FSQDFELNADMMMLISGI-GIVINIVMMFVLH- 256
            .|.||:|||::.:   |:|.|...:.:|.:  .::...::...::||.|: |:::|:|.:.:..
Human    75 ARAEVVGALSNAV---FLTALCFTIFVEAVLRLARPERIDDPELVLIVGVLGLLVNVVGLLIFQD 136

  Fly   257 -GSWFVNGNGHGHSHSHSHSHSHSHG----------NGHEPNDSLSQTRSNSNFLTTIGSQSAST 310
             .:||.... .|.|.........:.|          ...:|..:...|...|:...|:...|...
Human   137 CAAWFACCL-RGRSRRLQQRQQLAEGCVPGAFGGPQGAEDPRRAADPTAPGSDSAVTLRGTSVER 200

  Fly   311 ADEE----------DSIRKEINSNEHKIVITNGKKPTLTGTSNMELAHEDKNLNLRAAMIHVIGD 365
            ..|:          ||...:   ||.:.::...||              .:.||:|..::||:||
Human   201 KREKGATVFANVAGDSFNTQ---NEPEDMMKKEKK--------------SEALNIRGVLLHVMGD 248

  Fly   366 LVQSIGVFLAAVLIKV--------CPGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQN 422
            .:.|:.|.:.|::..|        |....|.||..|::..||::.:...|.:|:..|::..||:.
Human   249 ALGSVVVVITAIIFYVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIKETAAILLQMVPKG 313

  Fly   423 LNMRTLHLELGSIEGVRSLHHLNVWQQTSQQRVLMVHL-------VTDSRADGNEVLQAATALVS 480
            :||..|..:|.::.|:.|:|.:::|:..|.:.:..:|:       ..|:.....|:...|
Human   314 VNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQDASTKIREIFHHA----- 373

  Fly   481 SPRYNIKHSTIQLE 494
                .|.:.|||.|
Human   374 ----GIHNVTIQFE 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT41F	NP_610185.1	CDF	142..495	CDD:273544	93/394 (24%)
		Cation_efflux	142..416	CDD:279834	73/307 (24%)
SLC30A10	NP_061183.2	CzcD	10..383	CDD:224151	93/402 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..196		4/28 (14%)
		Required for plasma membrane localization. /evidence=ECO:0000269|PubMed:25319704	308..485		20/85 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810