Protein Alignment ZnT41F and slc30a8

DIOPT Version :10

• Sequence 1: NP_610185.1
• Gene: ZnT41F / 35513
• FlyBaseID: FBgn0025693
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001011041.1
• Gene: slc30a8 / 496450
• XenbaseID: XB-GENE-958127
• Length: 374
• Species: Xenopus tropicalis
• Alignment Length: 414
• Identity: 129/414 - (31%)
• Similarity: 206/414 - (49%)
• Gaps: 89/414 - (21%)

  Fly    93 DSARNQSSETEFDMQRECCNHQPGFRANSKSKSAQE--------AKYKIMLAVALCCVFMIIEFL 149
            ||.:|..|:.....:.   |.|..:..::.:|.|.:        ||.|:.:|..:|.||:..|.:
 Frog    23 DSEKNHPSKPPLQDEE---NPQSKYHCHNNNKKAYDARQREQTFAKKKLCIASLICFVFISAEIV 84

  Fly   150 GGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWFVT 214
            |||:|||||::||||||..|..||.|.|.::|:..:....|::||:.|.|::|||.|::.||.||
 Frog    85 GGYIAGSLAVVTDAAHLLVDLSSFFISLCSLWLSSKSSTTRLTFGWHRAEILGALMSVITIWLVT 149

  Fly   215 TLLVVVAIERIFSQDFELNADMMMLISGIGIVINIVMMFVLHGSWFVNGNGHGHSHSHSHSHSHS 279
            .:||.:|.||:...|:.::..:|::.|...:..|:|:..:||.|      ||||||:
 Frog   150 GVLVYLACERLIRPDYTIDGTVMLITSACALGANLVLALILHQS------GHGHSHA-------- 200

  Fly   280 HGNGHEPNDSLSQTRSNSNFLTTIGSQSASTADEEDSIRKEINSNEHKIVITNGKKPTLTGTSNM 344
             |..||
 Frog   201 -GGKHE----------------------------------------------------------- 205

  Fly   345 ELAHEDK---NLNLRAAMIHVIGDLVQSIGVFLAAVLIKVCPGAKYADPLCTLIFSIIVIMTTLR 406
            .:|.|.|   |.::|||.|||||||.|||.|.::|::|...|..|.|||:||.||||.|::||:.
 Frog   206 HMASEYKPQTNASIRAAFIHVIGDLFQSISVLISALIIYFKPEYKMADPICTFIFSIFVLITTVT 270

  Fly   407 LFRESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTSQQRVLMVHLVTDSRADGNEV 471
            :.|:.|.:::...|:.::...:...:.:::||:|:|.|::|..|..|.:|..|:.||...:...:
 Frog   271 VLRDLLTVLMEGTPRGIHYSDVKQSILAVDGVKSVHSLHLWALTMNQVILSAHIATDIVGESKRI 335

  Fly   472 LQAATALVSSPRYNIKHSTIQLEP 495
            |:..|..|.: |:.....|||:||
 Frog   336 LKDVTQNVFA-RFPFHSVTIQVEP 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT41F	NP_610185.1	CzcD	132..495	CDD:440843	117/365 (32%)
slc30a8	NP_001011041.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..48		6/27 (22%)
		HCH Motif, seals regulatory zinc-binding pocket. /evidence=ECO:0000250|UniProtKB:Q8IWU4	45..47		0/1 (0%)
		CzcD	64..358	CDD:440843	119/368 (32%)