Protein Alignment ZnT41F and SLC30A8

DIOPT Version :9

• Sequence 1: NP_610185.1
• Gene: ZnT41F / 35513
• FlyBaseID: FBgn0025693
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_776250.2
• Gene: SLC30A8 / 169026
• HGNCID: 20303
• Length: 369
• Species: Homo sapiens
• Alignment Length: 450
• Identity: 133/450 - (29%)
• Similarity: 220/450 - (48%)
• Gaps: 104/450 - (23%)

  Fly    50 DYQDRYYSVNNNSVNREVVTIGSNVVRVPEEQTWEVPLLGDCGDSARNQSSETEFDMQRECCNHQ 114
            ::.:|.|.||:.:......|:.|  |.:.::     |:..|  ...|.:..|.|......|
Human     2 EFLERTYLVNDKAAKMYAFTLES--VELQQK-----PVNKD--QCPRERPEELESGGMYHC---- 53

  Fly   115 PGFRANSK--SKSAQE---AKYKIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFV 174
               .:.||  .|.|.|   ||:|:..|.|:|.:|||.|.:||::|||||::||||||..|..||:
Human    54 ---HSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFL 115

  Fly   175 IGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWFVTTLLVVVAIERIFSQDFELNADMMML 239
            :.|.::|:..:||.:|::||:.|.|::|||.|||.||.||.:||.:|.||:...|:::.|.:|::
Human   116 LSLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMII 180

  Fly   240 ISGIGIVINIVMMFVLHGSWFVNGNGHGHSHSHSHSHSHSHGNGHEPNDSLSQTRSNSNFLTTIG 304
            :|...:..|||:..|||....      ||:|
Human   181 VSSCAVAANIVLTVVLHQRCL------GHNH---------------------------------- 205

  Fly   305 SQSASTADEEDSIRKEINSNEHKIVITNGKKPTLTGTSNMELAHEDKNLNLRAAMIHVIGDLVQS 369
                          ||:.:                            |.::|||.:|.:|||.||
Human   206 --------------KEVQA----------------------------NASVRAAFVHALGDLFQS 228

  Fly   370 IGVFLAAVLIKVCPGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELGS 434
            |.|.::|::|...|..|.|||:||.||||:|:.:|:.:.::...:::..||::||...:...:.:
Human   229 ISVLISALIIYFKPEYKIADPICTFIFSILVLASTITILKDFSILLMEGVPKSLNYSGVKELILA 293

  Fly   435 IEGVRSLHHLNVWQQTSQQRVLMVHLVTDSRADGNEVLQAATALVSSPRYNIKHSTIQLE 494
            ::||.|:|.|::|..|..|.:|..|:.|.:..| ::|::...|...|..:.:...|||:|
Human   294 VDGVLSVHSLHIWSLTMNQVILSAHVATAASRD-SQVVRREIAKALSKSFTMHSLTIQME 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT41F	NP_610185.1	CDF	142..495	CDD:273544	108/352 (31%)
		Cation_efflux	142..416	CDD:279834	86/273 (32%)
SLC30A8	NP_776250.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..52		5/22 (23%)
		CDF	83..353	CDD:273544	108/352 (31%)
		Cation_efflux	83..274	CDD:279834	86/272 (32%)
		HXXXXX[HY]NH-motif	197..205		3/13 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53838
OrthoDB	1	1.010	-	-		D351752at33208
OrthoFinder	1	1.000	-	-		FOG0000470
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830