Protein Alignment ZnT41F and SLC30A7

DIOPT Version :9

• Sequence 1: NP_610185.1
• Gene: ZnT41F / 35513
• FlyBaseID: FBgn0025693
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001138356.1
• Gene: SLC30A7 / 148867
• HGNCID: 19306
• Length: 376
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 95/401 - (23%)
• Similarity: 173/401 - (43%)
• Gaps: 99/401 - (24%)

  Fly   117 FRANSKSKSAQEAKYKIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIW 181
            ||:....|:::...:.:.|.::    |..:|.|.|..:..|.:::|:.|:..|..:.:.||.|..
Human    26 FRSILSDKTSRNLFFFLCLNLS----FAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASV 86

  Fly   182 IGGRPPDERMSFGYKRFEVIGALASILGIWFVTTLLVVVAIERIFSQDFELNADMMMLISGIGIV 246
            |.....::..|:||.|.||:....:.|.:.|....:....:||..:.. :::.:.::|:|.:|.|
Human    87 ISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPP-DVHHERLLLVSILGFV 150

  Fly   247 INIVMMFVL-HGS-WFVNGNGHGHSHS----------------HS--------HSHSHSHGNGH- 284
            :|::.:||. ||. ...:|:|||||||                ||        |||.|:||:||
Human   151 VNLIGIFVFKHGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHF 215

  Fly   285 --EPNDSLSQTRSNSNFLTTIGSQSASTADEEDSIRKEINSNEHKIVITNGKKPTLTGTSNMELA 347
              ....||.:|                                             ||.|..
Human   216 HSHDGPSLKET---------------------------------------------TGPSRQ--- 232

  Fly   348 HEDKNLNLRAAMIHVIGDLVQSIGVFLAAVLIKVCPGAKYADPLCTLIFSIIVIMTTLRLFRESL 412
                  .|:...:|::.|.:.||||..:|::::.. |...|||:|:::.:|:::::.:.|.|||:
Human   233 ------ILQGVFLHILADTLGSIGVIASAIMMQNF-GLMIADPICSILIAILIVVSVIPLLRESV 290

  Fly   413 GIIVNAVPQNL--NMRTLHLELGSIEGVRSLHHLNVWQQTSQQRVLMVHLVTDSRADGNEVLQAA 475
            ||::...|..|  ::...:..:..::||.||...:.|...|...|..:.|:....||...:|
Human   291 GILMQRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWIL--- 352

  Fly   476 TALVSSPRYNI 486
                 |..:||
Human   353 -----SQTHNI 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT41F	NP_610185.1	CDF	142..495	CDD:273544	91/376 (24%)
		Cation_efflux	142..416	CDD:279834	75/302 (25%)
SLC30A7	NP_001138356.1	CzcD	31..374	CDD:224151	93/396 (23%)
		Cation_efflux	48..294	CDD:279834	75/301 (25%)
		His-rich loop	161..218		20/56 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..226		12/31 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810