Protein Alignment CG7791 and OCT1

DIOPT Version :9

• Sequence 1: NP_610183.1
• Gene: CG7791 / 35511
• FlyBaseID: FBgn0033038
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_012788.2
• Gene: OCT1 / 853724
• SGDID: S000001617
• Length: 772
• Species: Saccharomyces cerevisiae
• Alignment Length: 710
• Identity: 228/710 - (32%)
• Similarity: 347/710 - (48%)
• Gaps: 85/710 - (11%)

  Fly    40 FTHDDVGLFGMPELRSFEGFYLLRDNVESRTQELISEATSD-QRRRKMVDI--FDELSDSLCKVA 101
            |..:..|||..|.|.|.:|..........:.|||:.:..:| ....|:..|  .|.|||:||:|.
Yeast    70 FKKNKTGLFKNPYLTSPDGLRKFSQVSLQQAQELLDKMRNDFSESGKLTYIMNLDRLSDTLCRVI 134

  Fly   102 DLAEFVRIAHPQSRYTQAAEQACISICGMVESLNTHKPIYKALSHVVDH---GDKLPTSEVDRHV 163
            ||.||:|..||...:.:||:.....:...:..|||...:...|..|:::   ..||...|:  .|
Yeast   135 DLCEFIRSTHPDDAFVRAAQDCHEQMFEFMNVLNTDVSLCNILKSVLNNPEVSSKLSAEEL--KV 197

  Fly   164 SRLFLFDFEQCGIHLPEEERMRVVRLNDYILQLGQKFMSGAVQP---SV------LPRSQVPESF 219
            .::.|.|||:.||::..:.|.:.::|:..|..:||:|::....|   ||      |..|:| .:|
Yeast   198 GKILLDDFEKSGIYMNPDVREKFIQLSQEISLVGQEFINHTDYPGSNSVKIPCKDLDNSKV-STF 261

  Fly   220 -----------RNY-FPTSGENVIITGLCTNAENVQMREAAYRLYLQPSKSQEDLLRDLLLCRHE 272
                       :|| .||.|  .....|..:.||..:|:..:......|..|...|..|:..|..
Yeast   262 LLKQLNKDVKGQNYKVPTFG--YAAYALLKSCENEMVRKKLWTALHSCSDKQVKRLSHLIKLRAI 324

  Fly   273 LARSCGFDTYAHRALKGSTMEKPEVVREFIDELSEKLRPRADCDFALMSQMKRREGGK-----AD 332
            ||......:||...|:|...:.|:.|::||..|......:...:...::::|.::..|     .|
Yeast   325 LANLMHKTSYAEYQLEGKMAKNPKDVQDFILTLMNNTIEKTANELKFIAELKAKDLKKPLTTNTD 389

  Fly   333 ARAEV---WDTPYYTNQLRRQLFE------EHANEFLPYFSLGGCMEGLDNLLHALYGIRLQNTD 388
            ...::   ||..|||.    :.|:      .:|.|...||:||..::||.:|...:|||||:...
Yeast   390 EILKLVRPWDRDYYTG----KYFQLNPSNSPNAKEISYYFTLGNVIQGLSDLFQQIYGIRLEPAI 450

  Fly   389 LKPGEAWHNDIYKLAVVHEREGLLGYIYCDFYERVGKPNQDCHF----------------TIQGG 437
            ...||.|..|:.:|.|:.|.||::|.||||.:||.||.:...||                |||.|
Yeast   451 TDEGETWSPDVRRLNVISEEEGIIGIIYCDLFERNGKTSNPAHFTVCCSRQIYPSETDFSTIQVG 515

  Fly   438 KRMPDGSY-QLPVVVVMLGLAQPRWSGPTLLSP---------ARLDNLFHEMGHAMHSMLARTEH 492
            :. |||:| ||||:.::...:      |.|::.         :.::.|||||||||||||.||..
Yeast   516 EN-PDGTYFQLPVISLVCNFS------PILIASKKSLCFLQLSEVETLFHEMGHAMHSMLGRTHM 573

  Fly   493 QHVTGTRCSTDFAEVPSVLMEYFAGDPRVLRTFARHFQTHEPISEDMLRRLCASKNLFAASETQL 557
            |:::||||:|||.|:||:|||:||.|.|:|....:|:.|.|.|..|||:|...|.|.....||..
Yeast   574 QNISGTRCATDFVELPSILMEHFAKDIRILTKIGKHYGTGETIQADMLQRFMKSTNFLQNCETYS 638

  Fly   558 QVFYSALDQEYHGASARHGQSSTDTLRSVQDHYYGLPYV--DNTAWQLRFSHLVGYGAKYYAYLV 620
            |...:.|||.:|.........:.|.:.:.|.....|..:  |.:.|..||.||.||||.||:||.
Yeast   639 QAKMAMLDQSFHDEKIISDIDNFDVVENYQALERRLKVLVDDQSNWCGRFGHLFGYGATYYSYLF 703

  Fly   621 SKTIASWIWQTYFEANPFNRQAGEKYRAEILAHGGAVPSRKLVANFLQREMTPSVLADSL 680
            .:||||.||...||.:|::|:.|:|::..:|..||.....|.:|:.|:..|.....:|::
Yeast   704 DRTIASKIWYALFEDDPYSRKNGDKFKKHLLKWGGLKDPWKCIADVLECPMLEKGGSDAM 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7791	NP_610183.1	M3A_MIP	46..680	CDD:188996	227/702 (32%)
OCT1	NP_012788.2	M3A_MIP	76..763	CDD:341052	227/702 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341725
Domainoid	1	1.000	257	1.000	Domainoid score	I321
eggNOG	1	0.900	-	-		E1_COG0339
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4337
Inparanoid	1	1.050	313	1.000	Inparanoid score	I467
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53667
OrthoFinder	1	1.000	-	-		FOG0003975
OrthoInspector	1	1.000	-	-		oto99018
orthoMCL	1	0.900	-	-		OOG6_102110
Panther	1	1.100	-	-	LDO	PTHR11804
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R934
SonicParanoid	1	1.000	-	-		X2731
TreeFam	1	0.960	-	-
	15	14.790