Protein Alignment CG7791 and THOP1

DIOPT Version :9

• Sequence 1: NP_610183.1
• Gene: CG7791 / 35511
• FlyBaseID: FBgn0033038
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_003240.1
• Gene: THOP1 / 7064
• HGNCID: 11793
• Length: 689
• Species: Homo sapiens
• Alignment Length: 667
• Identity: 167/667 - (25%)
• Similarity: 280/667 - (41%)
• Gaps: 86/667 - (12%)

  Fly    61 LLRDNVESRTQELISEATSDQRRRKMVDI----FDELS--DSLCKVAD----------LAEFVRI 109
            |....:|.||:|||     :|.:|....:    |:::|  .:|..:||          :.:|.:.
Human    28 LSAQQIEERTRELI-----EQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQH 87

  Fly   110 AHPQSRYTQAAEQACISICGMVESLNTHKPIYKA---LSHVVDHGDKLPTSEVDRHVSRLFLFDF 171
            ..|......|:.:|...:......::..:.:|:.   |...|......|  |..|::.||....
Human    88 VSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRP--EAARYLERLIKLG- 149

  Fly   172 EQCGIHLPEEERMRVVRLNDYILQLGQKFMSGAVQPSV-LP-----RSQVPESFRN--------- 221
            .:.|:|||.|.:..:.|:...:..|...|.....:.:. ||     ...:||.|.|
Human   150 RRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGK 214

  Fly   222 ---------YFPTSGENVIITGLCTNAENVQMREAAYRLYLQPSKSQED---LLRDLLLCRHELA 274
                     |||       :...|...|..:..|.|:.     .:.:|:   :|::|:..|.:.:
Human   215 LKVTLKYPHYFP-------LLKKCHVPETRRKVEEAFN-----CRCKEENCAILKELVTLRAQKS 267

  Fly   275 RSCGFDTYAHRALKGSTMEKPEVVREFIDELSEKLRPRADCDFALMSQMKR----REGGKADARA 335
            |..||.|:|...|:.:..:..:.|..|:|||::||:|..:.:.|::.::||    |.|...|.|.
Human   268 RLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECERRGLPFDGRI 332

  Fly   336 EVWDTPYYTNQLRRQLFEEHANEFLPYFSLGGCMEGLDNLLHALYGIRLQNTDLKPGEAWHNDIY 400
            ..||..||.||:....:....|....||.:.....||..:...|.|:...:.:  ...|||.|:.
Human   333 RAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLGLAFHHEE--GASAWHEDVR 395

  Fly   401 KLAVVHEREG-LLGYIYCDFYERVGKPNQDCHFTIQGGKRMPDGSYQLPVVVVMLGLAQPRWSGP 464
            .........| ::|..|.|.|.|.||......|.:|.|....|||.|:.:..::....:|....|
Human   396 LYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAP 460

  Fly   465 TLLSPARLDNLFHEMGHAMHSMLARTEHQHVTGTRCSTDFAEVPSVLMEYFAGDPRVLRTFARHF 529
            :||....::..|||.||.||.:.::.|....:||....||.|.||.::|.:..:...|...:||:
Human   461 SLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHY 525

  Fly   530 QTHEPISEDMLRRLCASKNLFAASETQLQVFYSALDQEYHGASARHGQSSTDT----LRSVQDHY 590
            :|...:..::|.:|..|:..........|:..:.:||      |.|.|:..|.    .|..|: .
Human   526 RTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVDQ------ALHTQTDADPAEEYARLCQE-I 583

  Fly   591 YGLPYVDNTAWQLRFSHLV-GYGAKYYAYLVSKTIASWIWQTYF-EANPFNRQAGEKYRAEILAH 653
            .|:|....|.....|.||. ||.|:||.||.|:..:..::.|.| :....|.:.|..||:.||..
Human   584 LGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRP 648

  Fly   654 GGAVPSRKLVANFLQRE 670
            ||:..:..::..||.|:
Human   649 GGSEDASAMLRRFLGRD 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7791	NP_610183.1	M3A_MIP	46..680	CDD:188996	167/667 (25%)
THOP1	NP_003240.1	M3A_TOP	34..675	CDD:188994	166/661 (25%)
		Dcp	39..679	CDD:223416	163/656 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1976
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D642479at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.770