Protein Alignment CG7791 and Thop1

DIOPT Version :10

• Sequence 1: NP_610183.1
• Gene: CG7791 / 35511
• FlyBaseID: FBgn0033038
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_742072.2
• Gene: Thop1 / 64517
• RGDID: 68330
• Length: 687
• Species: Rattus norvegicus
• Alignment Length: 664
• Identity: 165/664 - (24%)
• Similarity: 278/664 - (41%)
• Gaps: 80/664 - (12%)

  Fly    61 LLRDNVESRTQELISEATSDQRRRKMVDIFDELSDSLCK-VAD----------LAEFVRIAHPQS 114
            |....:.:.|.:||.:......|....|..|...:|..| :||          :.:|.:...|..
  Rat    28 LSAQQIRALTTQLIEQTKCVYDRVGAQDFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPNK 92

  Fly   115 RYTQAAEQACISICGMVESLNTHKPIYKALSHVVDHGDKLPTS----EVDRHVSRLFLFDFEQCG 175
            ....|:.:|...:......::..:.:|:   .||...:|:|..    |..|::.||.... .:.|
  Rat    93 DIRAASTEADKKLSEFDVEMSMRQDVYQ---RVVWLQEKIPKDSLKPEAARYLERLIKLG-RRNG 153

  Fly   176 IHLPEEERMRVVRLNDYILQLGQKFMSGAVQPSV-LPRSQ-----VPESFRN------------- 221
            :|||::.:.::..:...:..|...|.....:.:. ||.::     :||.|.|
  Rat   154 LHLPQDTQEKIKNIKKRLSLLCIDFNKNLNEDTTFLPFTREELGGLPEDFLNSLEKTEDGKLKVT 218

  Fly   222 -----YFPTSGENVIITGLCTNAENVQMREAAYRLYLQPSKSQED---LLRDLLLCRHELARSCG 278
                 |||       :...|...|..::.|.|:.     .:.:|:   :|::|:..|.:.:...|
  Rat   219 LKYPHYFP-------LLKKCHVPETRRLLEEAFN-----CRCKEENCAILKELVSLRAQKSNLLG 271

  Fly   279 FDTYAHRALKGSTMEKPEVVREFIDELSEKLRPRADCDFALMSQMKRREGGKA----DARAEVWD 339
            |.|:|...|:.:..:..:.|..|:|||:.||:|..:.:.|::.::|..|..|.    |.|...||
  Rat   272 FRTHADYVLEMNMAKTSQTVATFLDELARKLKPLGEQERAVILELKEAECAKRGLPFDGRIHAWD 336

  Fly   340 TPYYTNQLRRQLFEEHANEFLPYFSLGGCMEGLDNLLHALYGIRLQNTDLKPG-EAWHNDIYKLA 403
            ..||.||:....:....|....||.:.....||..:...|.|:..   .|:.| .|||.|:...:
  Rat   337 MRYYMNQVEETRYRVDQNLLKEYFPMQVVTRGLLAIYQELLGLTF---TLEEGAAAWHEDVRLYS 398

  Fly   404 VVHEREG-LLGYIYCDFYERVGKPNQDCHFTIQGGKRMPDGSYQLPVVVVMLGLAQPRWSGPTLL 467
            |.....| .:|..|.|.|.|.||......|.:|.|....|||.||.:..::....:|....|:||
  Rat   399 VRDAASGEEIGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSRQLAIAAMVANFTKPTPDVPSLL 463

  Fly   468 SPARLDNLFHEMGHAMHSMLARTEHQHVTGTRCSTDFAEVPSVLMEYFAGDPRVLRTFARHFQTH 532
            ....::..|||.||.||.:.::.|....:||....||.|.||.::|.:..:...|...::|::|.
  Rat   464 QHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEKEPLMRMSQHYRTG 528

  Fly   533 EPISEDMLRRLCASKNLFAASETQLQVFYSALDQEYHGASARHGQSSTDT----LRSVQDHYYGL 593
            ....||:|.:|..|:...|......|:..:.:||      ..|.|:..|.    .|..|: ..|:
  Rat   529 GEAPEDLLEKLIKSRQANAGLFNLRQIVLAKVDQ------VLHTQTDVDPAEEYARLCQE-ILGV 586

  Fly   594 PYVDNTAWQLRFSHLV-GYGAKYYAYLVSKTIASWIWQTYF-EANPFNRQAGEKYRAEILAHGGA 656
            |....|.....|.||. ||.|:||.||.|:..:..::.|.| :....:.:.|..||..||..||:
  Rat   587 PATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLSPKVGMDYRTSILRPGGS 651

  Fly   657 VPSRKLVANFLQRE 670
            ..:..::..||.|:
  Rat   652 EDASTMLKQFLGRD 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7791	NP_610183.1	M3A_MIP	46..684	CDD:341052	165/664 (25%)
Thop1	NP_742072.2	M3A_TOP	34..672	CDD:341050	164/658 (25%)