DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7791 and oct1

DIOPT Version :9

Sequence 1:	NP_610183.1	Gene:	CG7791 / 35511	FlyBaseID:	FBgn0033038	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_593013.1	Gene:	oct1 / 2541640	PomBaseID:	SPAC1F3.10c	Length:	762	Species:	Schizosaccharomyces pombe

Alignment Length:	680	Identity:	203/680 - (29%)
Similarity:	334/680 - (49%)	Gaps:	57/680 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RINFTHD-DVGLFGMPELRSFEGFYLLRDNVESRTQELISEATSDQRRRKMVDIFDELSDSLCKV 100
            |.:|..| |.|...:.|..|        :..::..::|:.|.|.|  ...:|..||.:|:.||.|
pombe    68 RNHFLSDKDTGFLRLAETAS--------EKCKAVIEDLLLEDTED--GSIVVSKFDRISNLLCSV 122

  Fly   101 ADLAEFVRIAHPQSRYTQAAEQACISICGMVESLNTHKPIYKALSHVVDHGDKLPTSEVDRH-VS 164
            .||.||||.|||.......||:|...:..::.:||||:.:|:.|...:.....|..::.:.: |.
pombe   123 IDLFEFVRCAHPDKMVVMKAEEAYSYLFELMNTLNTHQGLYEKLKCSLQQTPTLKDTDPEAYTVG 187

  Fly   165 RLFLFDFEQCGIHLPEEERMRVVRLNDYILQLGQKFMSGAV-QPS---VLPRSQVPES---FRNY 222
            |:||.|||:.|::|...:|...|:.:.....||:.|.:.:: :|.   .:.:.::..|   |...
pombe   188 RVFLQDFEKSGVNLESSKRNSFVKKSSESATLGRAFFNNSMNRPQRYLTISKQRLAGSDPYFVRS 252

  Fly   223 FPTSGENVII--------TGLCTNAENVQMREAAYRLYLQPSKSQEDLLRDLLLCRHELARSCGF 279
            ...:.:|.|:        |....:..|..:|:..|....:.:..:.:||...|..:.|:|:..|.
pombe   253 LSKNDKNFIMIPTVGYEGTQALISVANPDVRKEIYMEGHKGTVEEVELLNSYLRSKAEVAKLVGK 317

  Fly   280 DTYAHRALKGSTMEKPEVVREFIDELSEKLRPRADCDFALMSQMKRREGGKADARA-EVWDTPYY 343
            .::|...|.......|:.|.||::.||.|...........::.||::|.......: :|||..||
pombe   318 SSFADLQLIDKMANAPKHVVEFLENLSLKNSSVLKKILNNLALMKKKELNLNFLPSFDVWDREYY 382

  Fly   344 TNQLRRQLFEEHAN------EFLPYFSLGGCMEGLDNLLHALYGIRLQNTDLKPGEAWHNDIYKL 402
            |.:.::.|..:..:      .:..:||:|..::||..|..:|||:|....|:.|||.||.|:.|:
pombe   383 TARYKQSLINQKPSLNPSITNYRRFFSVGTVIQGLSRLFSSLYGLRFVPADISPGEVWHPDVNKV 447

  Fly   403 AVVHEREGLLGYIYCDFYERVGKPNQDCHFTIQGGK---------------------RMPDGS-Y 445
            .|.:|.:.::|.||.|.:.|.||.:...||||:..:                     |:.|.. |
pombe   448 NVYNENDHVMGVIYFDLFARTGKTDGAAHFTIRSSRELDLTSFDDSISLGFDDATNIRVKDNKRY 512

  Fly   446 QLPVVVVMLGLAQPRWSGPTLLSPARLDNLFHEMGHAMHSMLARTEHQHVTGTRCSTDFAEVPSV 510
            |:||:.::....:.....||.|....:..|||||||||||:|..|::|::.||||:|||.|:||:
pombe   513 QIPVISLLCNFVRSSGMDPTFLDLWDVKTLFHEMGHAMHSILGHTKYQNLAGTRCATDFVELPSI 577

  Fly   511 LMEYFAGDPRVLRTFARHFQTHEPISEDMLRRLCASKNLFAASETQLQVFYSALDQEYHGASARH 575
            :||:|..:|.||..:||:..|..|:...:|......:|..|..:.|.|:..:.:||.:|......
pombe   578 IMEFFMSNPAVLPLYARYEGTEIPLPVQVLNHHNMVENSSAPLDLQSQICMAMVDQLFHSKVVLD 642

  Fly   576 GQ-SSTDTLRSVQDHYYGLPYVDNTAWQLRFSHLVGYGAKYYAYLVSKTIASWIWQTYFEANPFN 639
            .. :|.|.:.:|...:.|.......||.|:||||.||.|.||:|:....:||.|:...|..||.:
pombe   643 PSFNSIDEVTNVTRKFSGFESAPPAAWYLQFSHLYGYSATYYSYIFDTVLASLIFSKLFAGNPLS 707

  Fly   640 RQAGEKYRAEILAHGGAVPSRKLVANFLQR 669
            |:||||:|..||..||:....:.||..|::
pombe   708 REAGEKFRKAILRWGGSRSPWECVAEALEQ 737

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7791	NP_610183.1	M3A_MIP	46..680	CDD:188996	199/670 (30%)
oct1	NP_593013.1	Dcp	47..755	CDD:223416	203/680 (30%)
oct1	NP_593013.1	M3A_MIP	65..748	CDD:188996	203/680 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	241	1.000	Domainoid score	I450
eggNOG	1	0.900	-	-		E1_COG0339
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4337
Inparanoid	1	1.050	298	1.000	Inparanoid score	I609
OMA	1	1.010	-	-		QHG53667
OrthoFinder	1	1.000	-	-		FOG0003975
OrthoInspector	1	1.000	-	-		oto100505
orthoMCL	1	0.900	-	-		OOG6_102110
Panther	1	1.100	-	-	LDO	PTHR11804
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R934
SonicParanoid	1	1.000	-	-		X2731
TreeFam	1	0.960	-	-
	14	13.860