DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ap and Bx

DIOPT Version :9

Sequence 1:	NP_724428.1	Gene:	ap / 35509	FlyBaseID:	FBgn0267978	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	151	Identity:	56/151 - (37%)
Similarity:	78/151 - (51%)	Gaps:	13/151 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 CSGCGRQIQDRFYLSAVEKRWHASCLQCYACRQPL-ERESSCYSRDGNIYCKNDYYSFFG-TRRC 210
            |:|||:.||||:.|.|::..||..||:|..|...| |..|:.|::...:.||.||...|| |..|
  Fly    92 CAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGYC 156

  Fly   211 SRCLASISSNELVMRARNLVFHVNCFCCTVCHTPLTKGDQYGIIDALIYCRTHYSIAREGDTASS 275
            :.|...|.:.|:|||||..|:|:.||.|..|:.....||::.:.:..|.|...|    |.....:
  Fly   157 AACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDY----EERLVFA 217

  Fly   276 SMSATYPY------SAQFGSP 290
            || |.:|.      |...|||
  Fly   218 SM-ANHPMLKRHVSSLGQGSP 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ap	NP_724428.1	LIM1_Lhx2_Lhx9	148..201	CDD:188755	22/53 (42%)
		LIM2_Lhx2_Lhx9	206..264	CDD:188763	21/58 (36%)
		Homeobox	371..424	CDD:395001
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	22/53 (42%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	19/53 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	0.796	Domainoid score	I4515
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910