Protein Alignment ap and ttx-3

DIOPT Version :9

• Sequence 1: NP_724428.1
• Gene: ap / 35509
• FlyBaseID: FBgn0267978
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001257168.1
• Gene: ttx-3 / 181357
• WormBaseID: WBGene00006654
• Length: 409
• Species: Caenorhabditis elegans
• Alignment Length: 360
• Identity: 129/360 - (35%)
• Similarity: 174/360 - (48%)
• Gaps: 69/360 - (19%)

  Fly   132 SPESTSDSK--ITRN----------LDDCSGCGRQIQDRFYLSAVE-KRWHASCLQCYACRQPLE 183
            ||.|::||.  |.|.          |:.|..|...|.|: .:|.|: |.:|.:||:|..|..|.|
 Worm    82 SPSSSTDSNNLILRQIQIPKIEPALLNQCCLCTFAIVDK-EISVVDGKYYHNNCLRCQMCDIPFE 145

  Fly   184 RESSCYSRDGNIYCKNDYYSFFGTRRCSRCLASISSNELVMRARNLVFHVNCFCCTVCHTPLTKG 248
            ....||.|||...|:.|:...: .:.|.:|...::..::||:|:.::||..||.|.:|...|..|
 Worm   146 YSDKCYVRDGVFLCRADHAKRY-QKCCRKCEIPLNREDMVMKAKEMIFHHACFVCFICGIKLNPG 209

  Fly   249 DQYGII-DALIYCRTHYSIAREGDTASSSMSATYPYSAQFGSPHNDSSSPHSDPSRSIVPTGIFV 312
            |.|.:. ...:||..||:..|.......:..||.|  |....|
 Worm   210 DYYTMSPQGHLYCHAHYNAVRSTVLCEEAAVATVP--AVVAPP---------------------- 250

  Fly   313 PASHVINGLPQPARQKGRPRKRKPKDIEAFTANIDLNTEYVDFGRGSHLSSSSRTKRMRTSFKHH 377
            |........|.||..:..||:          |:.:......:.|.|   |.|.|:||||||||||
 Worm   251 PPPPTTTTAPPPAAPEQPPRE----------ASTEAEASTDEDGNG---SGSQRSKRMRTSFKHH 302

  Fly   378 QLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVLQVWFQNARAKWRRMMMKQDG----SGLLEKG 438
            |||.||:|||:||||||||||||:.||.|.||||||||||||||:||.:  .||    |.|....
 Worm   303 QLRAMKTYFALNHNPDAKDLKQLAAKTNLTKRVLQVWFQNARAKYRREL--HDGGRSSSPLCVSA 365

  Fly   439 E-GALDLD-----SISVHSPTSFILGGPNSTPPLN 467
            . .::|::     |.|.||...:.|    :||||:
 Worm   366 PLASMDMNPPLSSSSSGHSTDGYQL----NTPPLS 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ap	NP_724428.1	LIM1_Lhx2_Lhx9	148..201	CDD:188755	20/53 (38%)
		LIM2_Lhx2_Lhx9	206..264	CDD:188763	17/58 (29%)
		Homeobox	371..424	CDD:395001	44/52 (85%)
ttx-3	NP_001257168.1	LIM	110..163	CDD:259829	20/53 (38%)
		LIM	171..226	CDD:295319	17/54 (31%)
		Homeobox	296..348	CDD:278475	44/51 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165666
Domainoid	1	1.000	106	1.000	Domainoid score	I4120
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I2653
Isobase	1	0.950	-	0	Normalized mean entropy	S3827
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1174930at2759
OrthoFinder	1	1.000	-	-		FOG0002416
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105440
Panther	1	1.100	-	-	LDO	PTHR24208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3033
SonicParanoid	1	1.000	-	-		X1607
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.880