Protein Alignment ap and lim-4

DIOPT Version :10

• Sequence 1: NP_724428.1
• Gene: ap / 35509
• FlyBaseID: FBgn0267978
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_508669.1
• Gene: lim-4 / 180672
• WormBaseID: WBGene00002987
• Length: 355
• Species: Caenorhabditis elegans
• Alignment Length: 430
• Identity: 107/430 - (24%)
• Similarity: 165/430 - (38%)
• Gaps: 144/430 - (33%)

  Fly    53 LFRACSSSSCPDICDHS-TKPFGNAYGTESFRSYETADRATFEDSAAKFSISRSRTDCTEV---- 112
            |.:|..:|:..::.|.| |.||...|  .|..|..|:|..               :||:.:
 Worm     5 LVQAKKTSTASELSDSSLTFPFIGDY--LSSPSLTTSDYV---------------SDCSNLTVEG 52

  Fly   113 ----------SDET----TSGISFKTEPFGPPSSPESTSDSKITRNLDDCSGCGRQIQDRFYLSA 163
                      |||:    :|.:......|.|..:.....|:.|.    .|:.|..||||:|:||.
 Worm    53 PVPANQEFSSSDESSVYISSALRLADYAFTPDDNIRIKPDAVIV----ICTQCQHQIQDKFFLSI 113

  Fly   164 VEKRWHASCLQCYACRQPLERESSCYSRDGNIYCKNDYYSFFGTR----------RCSRCLASIS 218
            ..:.:|.:||||..|..||  .:.|:.:|...|||..|:....|.          :|:.|..:|.
 Worm   114 DGRNYHENCLQCSTCENPL--SNKCFYKDKTFYCKGCYFRTHVTSTASSCRELGPKCASCDRTIQ 176

  Fly   219 SNELVMRARNLVFHVNCFCCTVCHTPLTKGDQYGIIDALIYCRTHYSIAREGDTASSSMSATYPY 283
            :.:.|.||||.|:|:.||.|..|...|:.|::|.:.:..:.|:.|:....|||:..||..|
 Worm   177 ATDWVRRARNYVYHLACFSCNQCKRQLSTGEEYALQEGNLLCKQHFLELVEGDSGVSSQKA---- 237

  Fly   284 SAQFGSPHNDSSSPHSDPSRSIVPTGIFVPASHVINGLPQPARQKGRPRKRKPKDIEAFTANIDL 348
                                                                             
 Worm   238 ----------------------------------------------------------------- 237

  Fly   349 NTEYVDFGRGSHLSSSSRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVLQV 413
                             :|||:||:|...||..:::||..:.|||..||::::..|||.|||.||
 Worm   238 -----------------KTKRVRTTFAEDQLSVLQTYFNRDSNPDGADLEKIASMTGLSKRVTQV 285

  Fly   414 WFQNARAKWRRMMMKQDGSGLLEKGEGALDLDSISVHSPT 453
            ||||:||:.::...|.:|.      .|.....|:...||:
 Worm   286 WFQNSRARQKKWHQKSEGD------NGDSQRSSVGPSSPS 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ap	NP_724428.1	LIM1_Lhx2_Lhx9	148..201	CDD:188755	22/52 (42%)
		LIM2_Lhx2_Lhx9	206..264	CDD:188763	19/67 (28%)
		Homeodomain	368..424	CDD:459649	28/55 (51%)
lim-4	NP_508669.1	LIM	98..153	CDD:395333	23/56 (41%)
		LIM2_AWH	168..222	CDD:188765	18/53 (34%)
		Homeodomain	240..296	CDD:459649	28/55 (51%)