DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scaf and sphinx1

DIOPT Version :9

Sequence 1:	NP_610180.1	Gene:	scaf / 35505	FlyBaseID:	FBgn0033033	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_729255.2	Gene:	sphinx1 / 318005	FlyBaseID:	FBgn0052383	Length:	253	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	41/217 - (18%)
Similarity:	77/217 - (35%)	Gaps:	58/217 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   452 GAIIGDQFVLSSASCVNGLPVTDIRVKAGEWELGSTNEPLPFQLTGVKTVDVHPDYDPSTNSHDL 516
            |.||.:|::|:..        |.::....|..|.|......|.:..:...:....||   |.|.:
  Fly    58 GTIISNQWILTVK--------TVLKYSYIEVHLASRRSYRGFDIIRIYKENFRFHYD---NDHVI 111

  Fly   517 AII-----RLERRLE-------------FASHIQPICISDEDPKDSEQCFTSGWG--KQALSIHE 561
            |::     :.:||::             :..::..:|               |:|  |:...:.|
  Fly   112 ALVKCPYQKFDRRMDRVRVPAYDTRFERYVGNMTMVC---------------GYGTEKRHAKLPE 161

  Fly   562 EGALMHVTDTLPQARSECSADSS-----SVC-SATKFDS-CQFDVGSALACGSGSSVRLKGIFAG 619
               .|...:......:||:...:     .:| |...|.. |:.|:|.|:.....:...:..|:..
  Fly   162 ---WMRCIEVEVMNNTECAKYYTPLKWYEMCTSGEGFKGVCEGDIGGAVVTMGPNPTFIGIIWLM 223

  Fly   620 ENSCGEG-QTVRFAKPD-IKWI 639
            ..:|..| .:|.....| ||||
  Fly   224 PENCSIGYPSVHIRVSDHIKWI 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scaf	NP_610180.1	FtsK	<198..>334	CDD:332908
scaf	NP_610180.1	Tryp_SPc	428..616	CDD:238113	32/190 (17%)
sphinx1	NP_729255.2	Tryp_SPc	25..245	CDD:214473	39/215 (18%)
sphinx1	NP_729255.2	Tryp_SPc	26..248	CDD:304450	41/217 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435406
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030