Protein Alignment CG8245 and Tmem53

DIOPT Version :9

• Sequence 1: NP_610178.2
• Gene: CG8245 / 35503
• FlyBaseID: FBgn0033031
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_001272741.1
• Gene: Tmem53 / 68777
• MGIID: 1916027
• Length: 283
• Species: Mus musculus
• Alignment Length: 291
• Identity: 96/291 - (32%)
• Similarity: 147/291 - (50%)
• Gaps: 34/291 - (11%)

  Fly    47 LEYFIKFPKPSSKNEFVLAKDHDGEDS---------HVPIVMLLGWAGCQDRYLMKYSKIYEERG 102
            |:|.|:.|.....::   :.:.|.|::         ..|:|:||||.||:|:.|.|||.||.:||
Mouse     6 LDYSIEIPDQPCWSQ---SMEGDWEENRQGGKEAGKQQPVVILLGWGGCRDKNLAKYSAIYHKRG 67

  Fly   103 LITVRYTAPVDSLFWKRSEMIP----IGEKILKLIQDMNFDAHPLIFHIFSNGGAYLYQHINLAV 163
            .|.:|||||...:|:..|..||    |.:|:|:|:.|...:..||:||:|||.|..||:::...:
Mouse    68 CIVIRYTAPWHMVFFSESLGIPSLRVIAQKLLELLFDYEIEREPLLFHVFSNAGVMLYRYVLELL 132

  Fly   164 IKHK--SPLQVRGVIFDSAPGERRIISLYRAITAIYGREK---RCNCLAALVITITLSIMWFVEE 223
            ..|:  ..|.|.|.||||.||:..:|...||:..|..|..   |...|||..:.:.|
Mouse   133 QTHQRFRHLHVVGTIFDSGPGDSNLIGALRALATILERRPAVLRLLLLAAFALVVIL-------- 189

  Fly   224 SISALKSLFVPSSPVRPSPFCD-LKNEANRYPQLFLYSKGDIVIPYRDVEKFIRLRRDQGIQVSS 287
                ...|..|.:.:..:.|.| |::..:.:|:|:|||:.|.|:..||||:.:..|....:.|..
Mouse   190 ----FHFLLAPFTALFHTHFYDRLQDSGSCWPELYLYSRADKVVSARDVERMVEARLAHQVMVRG 250

  Fly   288 VCFEDAEHVKIYTKYPKQYVQCVCNFIRNCM 318
            |.|..:.||.....||..|.....:|:.||:
Mouse   251 VDFVSSAHVSHLRDYPTYYTSLCVDFMHNCV 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8245	NP_610178.2	DUF829	76..314	CDD:283384	87/247 (35%)
Tmem53	NP_001272741.1	DUF829	41..277	CDD:310367	87/247 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845424
Domainoid	1	1.000	147	1.000	Domainoid score	I4500
eggNOG	1	0.900	-	-		E1_KOG2521
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41573
Inparanoid	1	1.050	153	1.000	Inparanoid score	I4327
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55732
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002525
OrthoInspector	1	1.000	-	-		oto93169
orthoMCL	1	0.900	-	-		OOG6_103942
Panther	1	1.100	-	-	LDO	PTHR12265
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3675
SonicParanoid	1	1.000	-	-		X1896
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790