Protein Alignment Not3 and cnot3b

DIOPT Version :10

• Sequence 1: NP_610176.1
• Gene: Not3 / 35501
• FlyBaseID: FBgn0033029
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001428954.1
• Gene: cnot3b / 327627
• ZFINID: ZDB-GENE-030131-5838
• Length: 885
• Species: Danio rerio
• Alignment Length: 972
• Identity: 392/972 - (40%)
• Similarity: 529/972 - (54%)
• Gaps: 217/972 - (22%)

  Fly     1 MAATRKLQGEIDRCLKKVAEGVETFEDIWKKVHNATNTNQKQKHLQEKYEADLKKEIKKLQRLRD 65
            ||..||||||||||||||.||||.|||||||:|||.|.|||     ||||:||||||||||||||
Zfish     1 MADKRKLQGEIDRCLKKVTEGVEQFEDIWKKLHNAANANQK-----EKYESDLKKEIKKLQRLRD 60

  Fly    66 QIKSWIASAEIKDKSSLLENRRLIETQMERFKVVERETKTKAYSKEGLGAAQKMDPAQRIKDDAR 130
            |||:|:||.|||||..|:|||:||||||||||:||||||||||||||||.|||:||||:.|::..
Zfish    61 QIKTWVASNEIKDKRQLVENRKLIETQMERFKIVERETKTKAYSKEGLGLAQKVDPAQKEKEEVG 125

  Fly   131 NWLTSSISSLQIQIDQYESEIESL-LAGKKKRLDRDKQERMDDLRGKLDRHKFHITKLETLLRLL 194
            .|||::|.:|.:|:||:|||:||| :..:||:.|::||:|:::|:..::||:|||..|||:||:|
Zfish   126 QWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKEKQDRIEELKRLIERHRFHIRMLETILRML 190

  Fly   195 DNDGVEAEQVNKIKDDVEYYIDSSQEPDFEENEFIYDDIIGLDEVELSGTATTDSNNSNE----- 254
            |||.::.:.:.|||||||||:||||:||||||||:||| :.|:|:.|....|:.:.:.::
Zfish   191 DNDSIQVDSIRKIKDDVEYYLDSSQDPDFEENEFLYDD-LDLEEIPLPVVPTSPAGHPDDEIFQH 254

  Fly   255 TSGSPSSVTSGGSPSQSPVTVQQILNTSSQGAASSGSSAASAALFQQQLTAAQSNGNNVGYASDT 319
            :|.:|:|.||......||.|    ..|:|:.....|.|..| .:.|..:    .|||     ..:
Zfish   255 SSSTPTSTTSSSPIPPSPAT----CTTNSEDEKKRGHSTDS-EISQSPI----KNGN-----QSS 305

  Fly   320 SAASSSATTSTDPAGGTVAVNCVGGLADKRNKSSESNALKLKPQPHQLIKPTPVRATAKLPL--- 381
            |.:|||:.:|:.....::::..:..||...:.:|.|::|               .....:||
Zfish   306 SLSSSSSLSSSSSGASSISLISMATLASSGSSASGSSSL---------------LGNISVPLQNS 355

  Fly   382 ---SSDTQ---------------VNKIVSSTPSKNQQQLPTAASI---------VATSAMQSQSS 419
               ||.||               .:...:||.:.|...|||:.|.         ..|.:.|||::
Zfish   356 GSYSSATQQQTQQSQQQHQPKNSASSHSNSTSASNSILLPTSTSTSPPNTSTLGPLTPSSQSQTN 420

  Fly   420 IG-SCSSTGGTGASQSASSGNN------------------PGNNPAVQPNAPTPG--QSGIAAA- 462
            :| |.||:.|.|...||.:|.|                  .|:.||....|...|  .||:::|
Zfish   421 LGMSLSSSLGLGKGTSALTGTNQMPSLVLSGMPASLSGFLSGSTPAPYAQAAAAGCVGSGLSSAI 485

  Fly   463 ---AASTNVVSATIVSSANVQGQ--------------------SVIQPTPTIAFAAVAKHNTSLL 504
               .:|||  |:.:|:|....|.                    :.::|.|.:|.:.|....||..
Zfish   486 GTNISSTN--SSGVVTSLGTNGSLGSTSLLGSGSGILGLGSTFAAVEPLPLLAPSPVGSTLTSGS 548

  Fly   505 ENGPVLQQQLAVTPTVAAIVGAGTQAQQKHVPPLSNLQTNSPHIQNG-----LPVSDSTNDNSCN 564
            ..|.:  .....|...|...|:|||.:    ||      :.|. |||     ..|.|||:|:
Zfish   549 NVGVI--GSSGGTSGTANATGSGTQPR----PP------SGPK-QNGGSSYSAVVGDSTSDS--- 597

  Fly   565 VVDTISLKTMAQDAINRSAIDPNSLNQQQTSSIDLRQPQSQKSLLQHFNSETNTNQQQLTSQQQQ 629
                         |:|.::...||    |:||::|              :.||    ||......
Zfish   598 -------------ALNSASQSQNS----QSSSLNL--------------AVTN----QLMDSGSS 627

  Fly   630 QLQNNSLAATTGS---NNGTSTGSGLMNVANATGQPI---------------------------- 663
            .|.:.:||.::.|   :...:.|..|:|..::..||.
Zfish   628 LLGSMTLAPSSPSPVYSESKAGGGSLLNGPHSYTQPADTIKPQEPPSSLKSMAERVAQGSGLDGE 692

  Fly   664 ------------SGNAKTHACQPQQMATTEAHIPTLLGVTPLGPTPLQKEHQMQFQMMEAAYYHL 716
                        |..|.:......|::.:|..||..|||.||||.||.|:...|..|.|:|:.|:
Zfish   693 LSALHIPSDIFPSSTAPSGTPAAPQLSLSEVSIPPSLGVCPLGPVPLSKDQLYQQAMQESAWAHM 757

  Fly   717 PQPMDTEKLQTYFHRAPVLTPSHYPQAQMPIYDTVEFYQRLSTETLFFVFYYMEGSKAQYLAAKA 781
            |.|.|:|:::.|..|.|..|...:.|...|..|:||||||||||||||:|||:||:|||||||||
Zfish   758 PHPSDSERIRQYLMRNPCPTLPFHHQMPPPHSDSVEFYQRLSTETLFFIFYYLEGTKAQYLAAKA 822

  Fly   782 LKKQSWRFHTKYMMWFQRHEEPKIINDDYEQGTYIYFDYEKWSQRKKEGFTFEYKYLEDKEL 843
            |||||||||||||||||||||||.|.|::|||||||||||||.|||||||||||:||||::|
Zfish   823 LKKQSWRFHTKYMMWFQRHEEPKTITDEFEQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDL 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Not3	NP_610176.1	Not3	3..233	CDD:461155	157/230 (68%)
		PRK07764	<334..497	CDD:236090	50/237 (21%)
		NOT2_3_5	711..836	CDD:461199	89/124 (72%)
cnot3b	NP_001428954.1	None