Protein Alignment CG1344 and SCY1

DIOPT Version :10

• Sequence 1: NP_610175.2
• Gene: CG1344 / 35500
• FlyBaseID: FBgn0027507
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_011432.1
• Gene: SCY1 / 852797
• SGDID: S000003051
• Length: 804
• Species: Saccharomyces cerevisiae
• Alignment Length: 788
• Identity: 165/788 - (20%)
• Similarity: 293/788 - (37%)
• Gaps: 204/788 - (25%)

  Fly    20 TNQFWTVYNAKTPETTNDERCSQMLSVFEGKVF---------VKAHVWSNGVGPIERAIK----- 70
            |.:.|::|..:...:::.......:.:|:.|.|         :|:...|.....|:.|.:
Yeast    23 TAEPWSIYTGRPKSSSSSSPSKVSIFMFDKKQFENYLLHYGIIKSKSGSRDKVLIQEAYEILRNQ 87

  Fly    71 --NLMVYRHPYILKYIATWEKSGRKYL-ATERVRPLDEVLAQQTD--------------IEVCLG 118
              ||...:||.||..|...|:..:.:: .||.|....|.:.::||              |.|..|
Yeast    88 ANNLAKLKHPNILTLIEPLEEHSKNFMFVTEFVTSSLETVFRETDDEEQNFLQGHVKDNIVVQRG 152

  Fly   119 LRTILCALIFLVEKALARHLNINTQSIYVTESGSWRLAGFEYVWR---ATDVNKQLL-------- 172
            :..::.||.|:..:|...||||..::|::.|:..|:::|..|:.:   .|:.::..|
Yeast   153 ILQLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISGLGYLVKIPPGTNTSEYFLPQYDPRVP 217

  Fly   173 DLAHSFIDLT---IHGEN---FEQFFFS-------ILCEKVLSRKGTDSCITDSTPHVHEFREYC 224
            ...|..::.|   |..||   |:..:||       :...|.|.|  :::..::.....::|....
Yeast   218 PFMHLQLNYTAPEIVFENTLTFKNDYFSLGLLIYFLYTGKDLFR--SENSTSEYKLEYNKFESKI 280

  Fly   225 ST------------HLKHQNTKLRPR--------LSAILLHPYFNHEFVLIHSFLFELPLKSVHE 269
            ||            .|:|...||..|        ::.||...:|....|...:||.:||.|:..|
Yeast   281 STMSWDNIFSKVPQKLRHCIPKLINRDIYSRYDNITLILDSEFFQDPLVKTLNFLDDLPTKNNEE 345

  Fly   270 RHKFFRSLIDRLRYFDEEVVASQ---LACDLLSRMVLLDPAAQEFVTPHI-LRTKVTDKAPASLF 330
            ::.|...|::.|..|...::..:   :..:|||:.......:.:.|...: |..|:........|
Yeast   346 KYVFLEGLVNLLPEFPPALLQKKFLPILLELLSQFCAEKVVSDKCVGKSLDLIIKIGSTLSQLSF 410

  Fly   331 SPQIYVQYL----MPHILKMFRLRDAQIRLI-LLDYFMDYVRLLSDEQLESEILPHLQLGMNDT- 389
            ..::|...|    .|.:||     .|.|.|| .||.....|:  ..:.||:.:.|.....::|:
Yeast   411 QEKVYPVLLSDANFPVLLK-----KATICLIDNLDTLKQKVK--RSDFLENILKPLFNYVLHDSE 468

  Fly   390 NDVLVGKTLRCMADLVS-ILGANKVLGGDRAR-------------------------CFSDGRPH 428
            :|:    |:.|...|:| |..|.:||.....:                         ||.....|
Yeast   469 SDI----TVVCQEKLLSQIPLALEVLDFPTVKQFLLPLLSNLFTKTTSLTVKNTCVTCFQIMIEH 529

  Fly   429 AAVS--RDSNNPYP--------EPRSISPLMNTRSFD------VEDFMVSGSPLPQESNASPLS- 476
            .::.  ..|....|        :||.:|.|:  :.|:      .::.::....||...|.|..|
Yeast   530 KSIDSYTCSETVLPLFKSMKTRDPRILSKLL--KLFETVPLIITDEIVLVDQVLPLMWNYSMAST 592

  Fly   477 IRLSPDGGEDEKLRLNSNEKSISI-KHNI--------DPEKDSY--------ISGTEHERVA--N 522
            :..|...|..:.:    |:.|..| ||:|        |..:|::        :...:.|.||  |
Yeast   593 LTKSQYSGYTKAI----NKMSSDIQKHHIAKLDDKVNDIGEDAFHKVIEPTIMKKEDPETVAAKN 653

  Fly   523 ID-------EEGTWLDWDNTDHLQQGYQVDHAVTDSETN---SNSFAREIQTGKSLSPSYRTGKC 577
            |:       ::.|...:..|  |.|...:.::...:..|   :..|...|......:||.|||..
Yeast   654 IEVAAMQPVKKKTGSSYGET--LPQSKSILNSKPLNPKNALATRGFPTRILNSPPQTPSSRTGSK 716

  Fly   578 NLSVGVNETISQTEQKVIDDLSELDIKVQTVIQRSEFNEFDFFKDMEPI--------IEIRTSTC 634
            .::.|.:...|.|             ||:     .|||||..|.....|        :.:.::..
Yeast   717 VMTKGGSNDASST-------------KVE-----EEFNEFQSFSSTGSIRQTSAPSDVWMNSTPS 763

  Fly   635 ETPEQISS 642
            .||...||
Yeast   764 PTPTSASS 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1344	NP_610175.2	Protein Kinases, catalytic domain	24..>170	CDD:473864	40/179 (22%)
SCY1	NP_011432.1	PK_SCY1_like	18..326	CDD:270913	64/304 (21%)