Protein Alignment CG1344 and scyl3

DIOPT Version :10

• Sequence 1: NP_610175.2
• Gene: CG1344 / 35500
• FlyBaseID: FBgn0027507
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_955951.1
• Gene: scyl3 / 323839
• ZFINID: ZDB-GENE-030131-2559
• Length: 768
• Species: Danio rerio
• Alignment Length: 814
• Identity: 204/814 - (25%)
• Similarity: 341/814 - (41%)
• Gaps: 191/814 - (23%)

  Fly     1 MGNEGSKLKGILVEENAVETNQFWTVYNAKTPETTNDERCSQMLSVFEGKVFVKAHVWSNGVGPI 65
            ||.|.|.|...::||..:......|:::|..       |..:..|||..|        .:....:
Zfish     1 MGAESSALPSCVLEEPLLTLPSGLTMFSALL-------RDGKPASVFVHK--------QDNEDKV 50

  Fly    66 ERAIKNLMVYRHPYILKYIATWEKSGRKYLATERVRPLDEVLAQQTDIEVCLGLRTILCALIFLV 130
            .:|.|:|...|||.:|::::...:.|..:|.||.|:||..:|...:..|:|.||..:|.||:||.
Zfish    51 NKAAKHLKTLRHPCLLRFLSCSVQDGGIHLVTEPVQPLKRLLDNLSAEEICAGLYDLLQALVFLH 115

  Fly   131 EKALARHLNINTQSIYVTESGSWRLAGFEYVWRATDVNKQLLDLAHSFIDLTI------------ 183
            ::..:.|.|:...|::|.|.|.|:|.|.|.|.:.::...:.|....:..:.:.
Zfish   116 DRGKSSHNNVCISSVFVGEDGHWKLGGMETVCKFSEATPEFLKSIQNVRENSAIPPEEKLEGFKT 180

  Fly   184 ----HGENFEQFFFSILCEKVLSRKGTDSCITDSTPHVHE-----FREYCSTHLKHQNTKLRPRL 239
                |..:.:.|.|.::.|.:|..         .|.||.:     .:......|...:.|.||.|
Zfish   181 LPEKHAHSRDAFSFGVMVEALLPL---------LTGHVSDDLLVSLKNMLQASLLTPDHKSRPSL 236

  Fly   240 SAILLHPYFNHEFVLIHSFLFELPLKSVHERHKFFRSLIDRLRYFDEEVVASQLACDLLSRMVLL 304
            |.:|.|.:|.::|:.|.:||..|.||:..|:::||:.|:||::...||::|::||..||:.:|..
Zfish   237 STLLTHNFFRNDFLDIMNFLKSLTLKNEEEKNEFFKFLLDRVQNLPEELIATRLAPKLLNSLVFA 301

  Fly   305 DPAAQEFVTPHILRTKVTDKAPAS---LFSPQIYVQYLMPHILKMFRLRDAQIRLILLDYFMDYV 366
            :|.|.:...||:|:.|......|.   |.|..:|.:|::||:||::::.:..:|::||.:...|.
Zfish   302 EPMAVKSFLPHLLQPKQDSSVNAGEECLLSLSLYRRYVVPHLLKLYKVNEEHVRMVLLSHIHVYA 366

  Fly   367 RLLSDEQLESEILPHLQLGMNDTNDVLVGKTLRCMADLVSILGANKVLGGDRARCFSDGRPHAAV 431
            .....|:|:.:|||.:.|||.||||.||..||:.:|.||.:|||..|:||:|.:.|....|:...
Zfish   367 EFFPLEELKKQILPQVLLGMRDTNDSLVAMTLQSLAVLVPLLGAQVVVGGERTKVFKRTTPNFTK 431

  Fly   432 SRDSNNPYPEPRSISPLMNTRSFDVEDFMVSGSPLPQESNASPLSIRLSPDGGEDEKLRL----- 491
            |.:..   ||   .||:           .:.||..|..|. .|..:.|...|.||:|:.|
Zfish   432 STEVT---PE---TSPV-----------HIVGSSHPHISQ-PPTVLNLFSKGSEDQKVVLENMYS 478

  Fly   492 -----NSNEKSISIKHNIDPEKDSYISGTE------HERVAN----IDEEGTWLDWDNTDHLQ-- 539
                 |:..:.||.:.....|....::|..      ..|.:|    .||:  |.:|.:|:.::
Zfish   479 FQAAENTTSEHISERTVFSSEMSFPLNGYRMSTQPVESRKSNGEVRTDED--WPNWSDTEEMEKD 541

  Fly   540 --QGYQVD----------------HAVTDSETNSNSFA-REIQTGKSLS-------PSYRTGKCN 578
              |..|:.                |...|.|...:.|. .|:.:.:|.|       |...|....
Zfish   542 KSQSVQISIQSAEIPDQRNSTIQAHKEDDGEEPWDDFEDSEVTSDQSPSTRLPVSVPKMSTKSTA 606

  Fly   579 LSVGV------------------------NETIS------QTEQKVIDDLSELDIKVQ------- 606
            ||:..                        |.|.|      |....:..:.:.|..:.:
Zfish   607 LSLSEPSAGPLRPSKALRLNPSMKSAPDHNHTSSWDTGWNQEANTLKPNKTSLSSEPRPKSTIRS 671

  Fly   607 ----------TVIQRSEFN---EFDFFKDMEPIIEIRTSTCETPEQISSRFA------------- 645
                      |:..:.:|.   |.|||.||.|.|::.:|:...|.:.|:..|
Zfish   672 PAAGSLGEEFTIAVKKKFEPDPELDFFADMIPDIKLSSSSLLLPVESSASVAVMGHVTSDPSIDT 736

  Fly   646 ----AAASAVNCNELCADQGWGHDEQDDKDDIVW 675
                |..:|.:..| ...:|||       ||:.|
Zfish   737 VSLTAKFAAADLTE-TETEGWG-------DDLKW 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1344	NP_610175.2	Protein Kinases, catalytic domain	24..>170	CDD:473864	42/145 (29%)
scyl3	NP_955951.1	Protein Kinases, catalytic domain	32..247	CDD:473864	58/231 (25%)
		HEAT repeat	339..367	CDD:293787	8/27 (30%)
		HEAT repeat	377..407	CDD:293787	17/29 (59%)