Protein Alignment hrm and SLC16A3

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001035887.1
• Gene: SLC16A3 / 9123
• HGNCID: 10924
• Length: 465
• Species: Homo sapiens
• Alignment Length: 627
• Identity: 127/627 - (20%)
• Similarity: 218/627 - (34%)
• Gaps: 225/627 - (35%)

  Fly    50 PDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSI 114
            |||||||.||.|..:.........|:..|.|.|....|....:..|||.::...:....||:.|:
Human    16 PDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSV 80

  Fly   115 LSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLR 179
            ...::..|.|.|:||..|||||:.:.:..||..:|::.||:.|:|..|:|.|::.::..||:|.|
Human    81 CVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRR 145

  Fly   180 GLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRA 244
            .:||||..:||.:....|.||.:.|.:.||:.|..||:||:.||..|.|....|:      |..|
Human   146 PMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPL------VVTA 204

  Fly   245 RQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAVV 309
            :                                    |.:.||.|
Human   205 Q------------------------------------PGSGPPRP-------------------- 213

  Fly   310 QSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRLS 374
                         ||::
Human   214 -------------SRRL------------------------------------------------ 217

  Fly   375 KRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQAQ 439
                                                                             
Human   218 ----------------------------------------------------------------- 217

  Fly   440 QPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATDL 504
                   .|||:.:|..:::..::.|...:......:.:.|:.:..|...:.:|:||:::...|:
Human   218 -------LDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDI 275

  Fly   505 IGRIGGSALSDMGYI-PKTWY-FVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYVGITA 567
            ..|.....::.:|.: |.:.| |...:..:||:......|..|..:..:|..||::.|:...:..
Human   276 FARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQF 340

  Fly   568 VIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGAS----- 627
            .::..::||.:.:|:.|:.|.:..:..|||||......:|.:.|..:|      :||||.
Human   341 EVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVF------ILAGAEVLTSS 399

  Fly   628 ----LWSFMPWINRRK--------ANAEEQLDAQIEKAAVDS 657
                |.:|  :..|:|        |.|||:   ::.|...||
Human   400 LILLLGNF--FCIRKKPKEPQPEVAAAEEE---KLHKPPADS 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	124/621 (20%)
		MFS	59..>234	CDD:119392	58/174 (33%)
		MFS	<449..633	CDD:119392	42/194 (22%)
SLC16A3	NP_001035887.1	2A0111	8..444	CDD:331689	127/627 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..438		7/21 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9818
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	6.020