Protein Alignment hrm and Slc16a3

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_110461.1
• Gene: Slc16a3 / 80878
• RGDID: 620603
• Length: 471
• Species: Rattus norvegicus
• Alignment Length: 658
• Identity: 129/658 - (19%)
• Similarity: 216/658 - (32%)
• Gaps: 252/658 - (38%)

  Fly    41 DDKEYDLVPPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLY 105
            |:....:..|||||||.||.|..:.........|:..|.|.|....|....:..|||.::...:.
  Rat     7 DEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSILLAML 71

  Fly   106 SSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYI 170
            ...||:.|:...::..|.|.|:||..|||||:.:.:..||..:|::.||:.|:|..|:|.|::.:
  Rat    72 YGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIM 136

  Fly   171 VTSYFAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVE 235
            :..||.|.|.:||||..:||.:....|.||.:.|.:.||:.|..||:||:.||..|.|....
  Rat   137 LNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMR--- 198

  Fly   236 QHMVRVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQF 300
                                                                 ||..|
  Rat   199 -----------------------------------------------------PLVAP------- 203

  Fly   301 VRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTL 365
                                                          |:|..|.|.|
  Rat   204 ----------------------------------------------QASGGAEPHG--------- 213

  Fly   366 RNSSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYA 430
                                                                             
  Rat   214 ----------------------------------------------------------------- 213

  Fly   431 DVDARGQAQQPQR--SKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSA 493
                      |||  .:..|||:.:|..:|:..::.|...:......:.:.|:.:..|...:.:|
  Rat   214 ----------PQRPSPRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAA 268

  Fly   494 YLLSVVSATDLIGRIGGSALSDMGYIPKTWYFVGGLSISGLSLALLPFAW--------------T 544
            :||:::...|:..|            |...:..|...:...|:.|..||.              .
  Rat   269 FLLTILGFIDIFAR------------PTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTASD 321

  Fly   545 YSSVCFWCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVN 609
            |..:..:|..||::.|:...:...::..::||::.:|:.|:.|.:..:..|:|||......:|..
  Rat   322 YGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATK 386

  Fly   610 DYNPLFHALGLTLLAGAS---------LWSFMPWINRRK----------ANAEEQL-----DAQI 650
            .|..:|      :||||.         |.:|. .|.:||          |:.||:|     |.::
  Rat   387 VYKYVF------ILAGAEVLTSSLVLLLGNFF-CIGKRKRPEVTKPEEVASEEEKLHKPPVDVRV 444

  Fly   651 EKAAVDSY 658
            :...|:.:
  Rat   445 DSREVEHF 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	127/643 (20%)
		MFS	59..>234	CDD:119392	58/174 (33%)
		MFS	<449..633	CDD:119392	41/206 (20%)
Slc16a3	NP_110461.1	MFS_MCT3_4	21..410	CDD:340988	113/599 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5173
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.920