Protein Alignment hrm and slc16a5b

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: XP_001919658.1
• Gene: slc16a5b / 794371
• ZFINID: ZDB-GENE-131120-181
• Length: 547
• Species: Danio rerio
• Alignment Length: 664
• Identity: 132/664 - (19%)
• Similarity: 240/664 - (36%)
• Gaps: 214/664 - (32%)

  Fly    20 HKPNGNTNESRHK-----------TVSLINKKDDKEYD----------------------LVPPD 51
            |:|..||..:|.:           |.|..:::.|:|.:                      .:.||
Zfish     8 HQPQPNTTVTRSRASSLQAFENADTASCKSEEPDQEEEEEQSSSTLPEERHCSTGGQANAQLAPD 72

  Fly    52 GGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSS 113
            |||||:|:..:.|.   .:..|..|   |:.::|....|.:|.|:.:|:||:...:..:.||:.|
Zfish    73 GGWGWVVVAATILVLAMTLAFPSCI---GIFYTELQSDFQASNTETSWVPAIMMAVLHACGPICS 134

  Fly   114 ILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKL 178
            :|..:...|...::||..:.|||..|.:|.::..|||:.|::.|:|..|.|.|::.:|..||.:.
Zfish   135 VLVERCGCRATIIIGGILSGLGMAASSFAQTMVELYITAGIITGMGFSLCFQPSITMVGHYFVRR 199

  Fly   179 RGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPR 243
            |..||.|..:|:|||..|||.|..:||..:|:.||.|::||:.||..|.
Zfish   200 RAFANALSSTGTALGLSILPLLANYLLRNFGWRGSFLVLGGVLLNCCVC---------------- 248

  Fly   244 ARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAV 308
                          |.||:                          ||             |:...
Zfish   249 --------------GAVMR--------------------------PL-------------AAKPK 260

  Fly   309 VQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRL 373
            .::.:|..|....:                                     :|.|::....|.||
Zfish   261 TETRTKETDNHHLK-------------------------------------TNCLSVHQGLKGRL 288

  Fly   374 SKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQA 438
            .....:..:||
Zfish   289 RATLSTIMTFL------------------------------------------------------ 299

  Fly   439 QQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATD 503
               :|...||| |..:|.:....:..|...:.:...::.|..:..|.|..:..:|.|::::...:
Zfish   300 ---RRHMAFDL-LCSNPYFCAYALGVSWMMLGFVVPLVYLVPYATAYGMEQDQAALLMAILGLIN 360

  Fly   504 LIGRIGGSALSDMGYIPK-------TWYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGI 561
            :|.|   .|.:.:..:|:       .:.|...:.|:|||..:.....::..:..:..|||.:..:
Zfish   361 IIVR---PATAIVFGLPRFRGSHNFAYLFAIAVVINGLSNCVCGIGTSFLVLLVYVILFGFSMSL 422

  Fly   562 YVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLT-LLAG 625
            ...:...::.|.:...|..|:.|:...:..::.|:||||.....::...|..:|.|..:| ..||
Zfish   423 VGSLLFTVLMDTVEMSRFPSALGLISIMESIMLLLGPPLAGILVDSTGQYIYVFFACSVTGSTAG 487

  Fly   626 ASLWSFMPWINRRK 639
            ..:.....|::||:
Zfish   488 LFIMLSFYWLDRRR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	123/602 (20%)
		MFS	59..>234	CDD:119392	58/177 (33%)
		MFS	<449..633	CDD:119392	36/191 (19%)
slc16a5b	XP_001919658.1	2A0111	71..511	CDD:331689	123/601 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.020