Protein Alignment hrm and Slc16a10

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001107804.1
• Gene: Slc16a10 / 72472
• MGIID: 1919722
• Length: 512
• Species: Mus musculus
• Alignment Length: 624
• Identity: 120/624 - (19%)
• Similarity: 213/624 - (34%)
• Gaps: 212/624 - (33%)

  Fly    48 VPPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPT-----KAAWIPALCYFLYSS 107
            |||:|||||||:|.:...|..:.|...::||||....|.|.:...     |.||:.:|...:...
Mouse    60 VPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLDTFKAKDDDNMAFKTAWVGSLSMGMIFF 124

  Fly   108 LGPVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVT 172
            ..|:.|:.:..:..|...::|.|...:|::.|.:.||||.||::||::...|...::.|::.|:.
Mouse   125 CCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILG 189

  Fly   173 SYFAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQH 237
            .||.|..||.||:..:||::.:|:||.||..|:.:.....:..|:......:|:|...|.|:
Mouse   190 HYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLISSVKLFNTLRILCIFMFVLFLAGFTYRPL--- 251

  Fly   238 MVRVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVR 302
               ||..:       |:|..|
Mouse   252 ---VPSTK-------EKESGG-------------------------------------------- 262

  Fly   303 SASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRN 367
                        |...|.|| ||:|.|
Mouse   263 ------------SRSSFFSR-RKLSPP-------------------------------------- 276

  Fly   368 SSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADV 432
                                                                             
Mouse   277 ----------------------------------------------------------------- 276

  Fly   433 DARGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLS 497
                       .|.|:.:|.|:..|.|...........|....:.|.:..:.|..:.:....|..
Mouse   277 -----------KKVFNFALFKETTYAVWAAGIPLALFGYFVPYVHLMNHVKERFQDVNNKEVLFM 330

  Fly   498 VVSATDLIGRIGGSALSDMGYIP---------KTWYFVGGLSISGLSLALLPFAWTYSSVCFWCA 553
            .:..|..:||:....::|  |:|         .:::|:|.:|:      ::|....:.::...|.
Mouse   331 CIGITSGVGRLLFGRIAD--YLPGVKKVYLQVLSFFFIGLMSM------MIPLCSAFGALIAVCL 387

  Fly   554 LFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHAL 618
            ..||..|.::.|.|.|..:::|.:..:.:.|..|....:...||||:.....:.:..|:..|:..
Mouse   388 AMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPIAGLLHDKLGTYDVAFYLA 452

  Fly   619 GLTLLAGASLWSFMPWINRRK-----ANA-EEQLDAQIE 651
            |:....|..:...:|||:.:|     .|| .|:::..:|
Mouse   453 GIPPFVGGVVLCLIPWIHSKKQRKISKNAGGEKMEKMLE 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	119/623 (19%)
		MFS	59..>234	CDD:119392	50/179 (28%)
		MFS	<449..633	CDD:119392	36/192 (19%)
Slc16a10	NP_001107804.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44
		2A0113	53..484	CDD:273325	118/615 (19%)
		MFS	68..467	CDD:119392	105/590 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820