Protein Alignment hrm and Slc16a14

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_082197.1
• Gene: Slc16a14 / 71781
• MGIID: 1919031
• Length: 512
• Species: Mus musculus
• Alignment Length: 619
• Identity: 147/619 - (23%)
• Similarity: 256/619 - (41%)
• Gaps: 150/619 - (24%)

  Fly    38 NKKDDKEYDLVPPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCY 102
            |||..|.:..:  ||||.|:::|.|...:|||.|:..:.|||..|:.:.|:.|....||:.:|..
Mouse    20 NKKTLKPHPDI--DGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSM 82

  Fly   103 FLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPT 167
            .:...:||...:.......|...::||...|||.:||.:|::::.|:|::||..|:|:|:::.|.
Mouse    83 GITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPA 147

  Fly   168 VYIVTSYFAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYE 232
            |.:|..||.|.|.||.||..:|:..|:.::..||::|...||:..:..|.|.::||:.|......
Mouse   148 VVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMR 212

  Fly   233 PVEQHMVRVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDER 297
            |:         :.:.|||.||.|:                                |..||.
Mouse   213 PL---------SPEKLENCPEAEE--------------------------------PCALPA--- 233

  Fly   298 LQFVRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPG------QLNSQSSLYAVPEG 356
                                 :.:.|.|...|:.:.: .|...||      .|.:|..     :|
Mouse   234 ---------------------YSTESVKSGGPLGMAE-EQDRRPGNEEMVCDLQTQEC-----QG 271

  Fly   357 RSSSNKLTLRNSSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGD 421
            ::...|                              :..:|:..:..|.|:::........|:|
Mouse   272 QTHPRK------------------------------NVCAFRVLKTVSQLTVQVRRGFRDWHSG- 305

  Fly   422 STGQDGSYADVDARGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFI---ILLPSFGE 483
                                   .|...||..:.|::..:.   ....:|::|:   |.||....
Mouse   306 -----------------------YFGTASLFTNRMFVAFIF---WALFAYSSFVIPFIHLPEIVS 344

  Fly   484 ARGFNKSLSAY-LLSVVSATDLIGRIGGSALSDMGYIPKTW--YFVGGLSISGLSLALLPFAWTY 545
            ....::....: |.|:::...:.|::...|::|:..| ..|  :.:...::. ||:.|||...||
Mouse   345 LYNLSEQNDTFPLTSIIAILHIFGKVILGAVADLPCI-SVWNVFLIANFTLV-LSIFLLPLMHTY 407

  Fly   546 SSVCFWCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVND 610
            :|:...|||.|.:|| |..:..|:..|::|||.|.::|||.:..||:..|:|||...:.|:....
Mouse   408 ASLAVICALIGFSSG-YFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQK 471

  Fly   611 YNPLFHALGLTLLAGASLWSFMPWI-----NRRK 639
            |:..|:..||..:.|.......|.|     :|||
Mouse   472 YDFSFYICGLLYMVGILFLLIQPCIQMIDQSRRK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	143/608 (24%)
		MFS	59..>234	CDD:119392	56/174 (32%)
		MFS	<449..633	CDD:119392	51/189 (27%)
Slc16a14	NP_082197.1	MFS_MCT14	35..494	CDD:340987	134/589 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810