Protein Alignment hrm and slc16a7

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001032485.1
• Gene: slc16a7 / 641419
• ZFINID: ZDB-GENE-051113-248
• Length: 465
• Species: Danio rerio
• Alignment Length: 621
• Identity: 134/621 - (21%)
• Similarity: 234/621 - (37%)
• Gaps: 194/621 - (31%)

  Fly    49 PPDGGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGP 110
            ||||||||.|:.||.::   :...|   ||..:.|.|..:.|:.|.::.||:.::......:.||
Zfish    13 PPDGGWGWAVVFGSFISIGFSYAFP---KSLTIYFKEIQEYFSISYSQIAWVSSIMLATMYAGGP 74

  Fly   111 VSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYF 175
            |||||..:|..|.|.:.||....:.|:.:.:.:||..||:..||:.|.|......|.:.|:..||
Zfish    75 VSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFGLAFDLQPALTIIGKYF 139

  Fly   176 AKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVR 240
            ...|.:|||:.::||.:....|.|:.::|.:.:|:.||..|:||:..|..||.....|     ::
Zfish   140 LVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMRP-----IK 199

  Fly   241 VPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSAS 305
            :|.::...:||
Zfish   200 IPVSKTTEDNI------------------------------------------------------ 210

  Fly   306 AAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSK 370
                                                                             
Zfish   211 ----------------------------------------------------------------- 210

  Fly   371 SRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDAR 435
                  ||.|:                                          |||      |::
Zfish   211 ------SPQTA------------------------------------------GQD------DSK 221

  Fly   436 GQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVS 500
            ......:.::|.|:||.|...:|:.|:.|......:...::.|..:.:.:|.::..:|:|||:.:
Zfish   222 PSGCSSKLNQFIDISLFKHRGFLIYLVGNVLMFFGFFAPVVFLAPYAKHQGVDEYSAAFLLSIFA 286

  Fly   501 ATDLIGRIGGSALSDMGYI-PKTWYFVG-GLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYV 563
            ..|:..|.|...:::..:| ||..||.. .::.:||...:.|....|..:..:..|||||.|:..
Zfish   287 LVDMFARPGTGLVANTKWIRPKIQYFFSFAVTYNGLCHLMCPLLPGYIGLVVYAVLFGLAFGMVC 351

  Fly   564 GITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASL 628
            .:...::.|::|.:|.:|:.|::..:.....|:|||:.....:...||..::.|.|:.:|||...
Zfish   352 ALLFEVLMDLVGAQRFSSAVGLATIIECGPVLLGPPISGLLVDIFMDYKYMYFACGMMMLAGGVF 416

  Fly   629 WSFMPWINRR-------KANAEE-QLDAQIEKAAVD 656
            ...|.:.|.|       :.|||| |:.:..|.||:|
Zfish   417 LFIMNYYNYRWLKKEEKQRNAEELQIFSTKELAAID 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	131/616 (21%)
		MFS	59..>234	CDD:119392	54/177 (31%)
		MFS	<449..633	CDD:119392	46/185 (25%)
slc16a7	NP_001032485.1	2A0113	1..440	CDD:273325	128/607 (21%)
		MFS	20..420	CDD:119392	115/580 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H77179
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.820