Protein Alignment hrm and slc16a7

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001032485.2
• Gene: slc16a7 / 641419
• ZFINID: ZDB-GENE-051113-248
• Length: 465
• Species: Danio rerio
• Alignment Length: 621
• Identity: 139/621 - (22%)
• Similarity: 237/621 - (38%)
• Gaps: 194/621 - (31%)

  Fly    49 PPDGGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGP 110
            ||||||||.|:.||.::   :...|   ||..:.|.|..:.|:.|.::.||:.::......:.||
Zfish    13 PPDGGWGWAVVFGSFISIGFSYAFP---KSLTIYFKEIQEYFSISYSQIAWVSSIMLATMYAGGP 74

  Fly   111 VSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYF 175
            |||||..:|..|.|.:.||....:.|:.:.:.:||..||:..||:.|.|...:..|.:.|:..||
Zfish    75 VSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFGLAFNLQPALTIIGKYF 139

  Fly   176 AKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVR 240
            ...|.:|||:.::||.:....|.|:.::|.:.:|:.||..|:||:..|..||.....|     ::
Zfish   140 LVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMRP-----IK 199

  Fly   241 VPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSAS 305
            :|.::...:||.
Zfish   200 IPVSKTTEDNIS----------------------------------------------------- 211

  Fly   306 AAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSK 370
                                       ||     |.||..|:      |.|.||  ||
Zfish   212 ---------------------------PQ-----TAGQDESK------PSGCSS--KL------- 229

  Fly   371 SRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDAR 435
                                                                             
Zfish   230 ----------------------------------------------------------------- 229

  Fly   436 GQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVS 500
                    ::|.|:||.|...:|:.|:.|......:...::.|..:.:.:|.::..:|:|||:.:
Zfish   230 --------NQFIDISLFKHRGFLIYLVGNVLMFFGFFAPVVFLAPYAKHQGVDEYSAAFLLSIFA 286

  Fly   501 ATDLIGRIGGSALSDMGYI-PKTWYFVG-GLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYV 563
            ..|:..|.|...:::..:| ||..||.. .::.:||...:.|....|..:..:..|||||.|:..
Zfish   287 LVDMFARPGTGLVANTKWIRPKIQYFFSFAVTYNGLCHLMCPLLPGYIDLVVYAVLFGLAFGMVC 351

  Fly   564 GITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASL 628
            .:...::.|::|.:|.:|:.|::..:.....|:|||:.....:...||..::.|.|:.:|||...
Zfish   352 ALLFEVLMDLVGAQRFSSAVGLATIIECGPVLLGPPISGLLVDIFMDYKYMYFACGMMMLAGGVF 416

  Fly   629 WSFMPWINRR-------KANAEE-QLDAQIEKAAVD 656
            ...|.:.|.|       :.|||| |:.:..|.||:|
Zfish   417 LFIMNYYNYRWLKKEEKQRNAEELQIFSTKELAAID 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	57/178 (32%)
		MFS	<451..633	CDD:475125	45/183 (25%)
slc16a7	NP_001032485.2	2A0113	1..440	CDD:273325	133/607 (22%)