Protein Alignment hrm and slc16a4

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001074068.2
• Gene: slc16a4 / 567144
• ZFINID: ZDB-GENE-070112-602
• Length: 558
• Species: Danio rerio
• Alignment Length: 643
• Identity: 158/643 - (24%)
• Similarity: 278/643 - (43%)
• Gaps: 124/643 - (19%)

  Fly    18 KDHKPNGNT-----NESRHKTVSLINKKDDKEYDLVPPDGGWGWLVLLGSCLTNILIPGTIKSFG 77
            |:...:|.|     :|.:.|   ::.|:..|.....||||||||:|:|...|.|:|:.||:|:||
Zfish     4 KEQHSDGKTAKTPCSELKAK---VMKKEKKKVVYREPPDGGWGWMVVLHCFLVNVLVMGTLKTFG 65

  Fly    78 VLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFWA 142
            :.|....|.|..|....:||.::...|..|.||::|:...|...|..:::|....|.|.:.|.:|
Zfish    66 IFFVALQDEFGGSSESISWIGSIMSSLRLSGGPLASVACAKLGNRVTSIVGALFVSAGFLFSIFA 130

  Fly   143 SSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLRGLANGLCISGSALG-SIILPPLLRWLLE 206
            :|:.:||||.|::||:|..|.:..|..::.:||.|  .||....|..|.:| :..|.|..:.||:
Zfish   131 TSVTYLYISMGLVVGLGFALLYQATSVVIVTYFRK--RLATAYSIGRSGMGLTFALAPFTQLLLD 193

  Fly   207 TYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRARQALENIPEEEDIGIVMKFENVDEPVP 271
            .|.:.|:.||:||:.||:..:.:...|:.   :|.|.:..:...|.:.|           .:|:.
Zfish   194 QYAWQGALLILGGLMLNLVASGMLLRPIN---IRHPASPISNSTIHKTE-----------KDPLK 244

  Fly   272 KNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRN 336
            .|...:.|                            |....|||..         |.|:   .::
Zfish   245 NNMNGNTP----------------------------VANGTSKSDS---------SPPI---HKD 269

  Fly   337 QTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKE 401
            .......::.|:||..:...:.:.|.:   |.:.|..:|.||..:....|
Zfish   270 TLIIKNPVHEQNSLPHLDLKKPTQNGV---NGTDSSQTKTSPEMNGVSPV--------------- 316

  Fly   402 FSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQAQQPQRS-KFFDLSLLKDPMYLVILISNS 465
                               ||..::|...:|        |:.| |..|.||||:|.:.:.
Zfish   317 -------------------DSLLENGRTENV--------PENSPKVLDFSLLKNPFFCIY----- 349

  Fly   466 TNAISYTNFIILLPSF---GEAR--GFNKSLSAYLLSVVSATDLIGRIGGSALSDMGYIPKTWYF 525
            |.::.::.....:|.|   ..||  |.:...:::::||...|:.:.::....::|...:.|..|.
Zfish   350 TWSLVFSQLAYFIPYFHLSARARNLGIDPMDASFIISVAGITETVAQLASGWVTDRNLVHKYHYH 414

  Fly   526 VGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVN 590
            ...|.:.|:...|.|.|.:|..:..:...|.:..|.|:.:...::.|::|.::|.:|.|.|:|..
Zfish   415 KAYLILCGVVNLLSPLATSYILLMVYAVFFAIFCGGYMALLLPVLVDLVGADKLNNSMGFSMFFV 479

  Fly   591 GLLQLVGPPLCNYWFEAVNDYNPLFHALGLT-LLAGASLWSFMPWINRRKANAEEQLD 647
            ||..|.||||..:.::....|:..|:..|:. ||:..||  |:..:.||....:|:|:
Zfish   480 GLGCLTGPPLAGFLYDYTQTYDCSFYLAGVCYLLSSISL--FLEPLARRWQARKERLE 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	151/607 (25%)
		MFS	59..>234	CDD:119392	58/175 (33%)
		MFS	<449..633	CDD:119392	48/189 (25%)
slc16a4	NP_001074068.2	2A0113	35..520	CDD:273325	146/592 (25%)
		MFS	47..520	CDD:119392	137/580 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920