Protein Alignment hrm and slc16a5a

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: XP_021336012.1
• Gene: slc16a5a / 565514
• ZFINID: ZDB-GENE-121108-4
• Length: 506
• Species: Danio rerio
• Alignment Length: 639
• Identity: 119/639 - (18%)
• Similarity: 211/639 - (33%)
• Gaps: 203/639 - (31%)

  Fly    38 NKKDDKEYDLVPPDGGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPA 99
            |......||  .|||||||:|||.:.:.   .:..|..|..|   :.:....|.::.::.:|:|:
Zfish    34 NANAPDSYD--APDGGWGWVVLLATIIVLALTLAFPSCIIIF---YLDLQKEFEATNSQTSWVPS 93

  Fly   100 LCYFLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSF 164
            :...:..:.||:.|:|..::..|...:.||..:..||.:|.::.||..|||:.||:.|:|...||
Zfish    94 IMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFSHSIVDLYITAGVITGLGFCFSF 158

  Fly   165 PPTVYIVTSYFAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAAL 229
            .|.|.|:..||.:.|..||.:..:|:|||...||.|..:|....|:.||.|::|.:.||..|...
Zfish   159 QPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIELGWRGSFLVLGAVLLNCCVCGA 223

  Fly   230 FYEPVEQHMVRVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPG 294
            ...|:..   |.||....:.|.|:..|
Zfish   224 VMRPIRP---RKPRKTNEINNSPKTSD-------------------------------------- 247

  Fly   295 DERLQFVRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSS 359
                  .:.....:.||.:.|                            |..|.:
Zfish   248 ------KKGCMLGICQSLASS----------------------------LRQQMA---------- 268

  Fly   360 SNKLTLRNSSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTG 424
                                                                             
Zfish   269 ----------------------------------------------------------------- 268

  Fly   425 QDGSYADVDARGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNK 489
                                  ||| ...:..:.|..:..:...:.:...:|.|..:..|...:.
Zfish   269 ----------------------FDL-FCSNTRFRVFSLGITWMMLGFVVPLIYLVPYASADDMDP 310

  Fly   490 SLSAYLLSVVSATDLIGRIGGSALSDMGYIPKTWY-------FVGGLSISGLSLALLPFAWTYSS 547
            |.:|.|||::...::..|.....|..:     .|:       |...|.|:|||.::...:.::..
Zfish   311 SRAALLLSILGFVNIFVRPPVGVLFSL-----PWFKGRHIYVFSAALLINGLSNSICCISASFPV 370

  Fly   548 VCFWCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYN 612
            :..:...:||:..:...:...::.|.:...|..|:.|:...:..:..|:||||..:..:....|.
Zfish   371 LLVYVLTYGLSMSVVGSLMFTVLMDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVDRTQLYT 435

  Fly   613 PLFHALGLTLLAGASLWSF-MPWINRRKANAEE---------QLDAQIEKAAVD 656
            .:|.|..:.::..|....| ..|::.|.|..::         ..|.|.....:|
Zfish   436 YVFMACTIIVVLSALFLMFTFYWLDSRDAAKKDSPAKPAINISTDCQYSSVPID 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	115/623 (18%)
		MFS	59..>234	CDD:119392	53/177 (30%)
		MFS	<449..633	CDD:119392	35/191 (18%)
slc16a5a	XP_021336012.1	2A0111	38..457	CDD:331689	112/601 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.920