Protein Alignment hrm and slc16a8

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001311456.1
• Gene: slc16a8 / 557884
• ZFINID: ZDB-GENE-121128-1
• Length: 453
• Species: Danio rerio
• Alignment Length: 608
• Identity: 136/608 - (22%)
• Similarity: 224/608 - (36%)
• Gaps: 179/608 - (29%)

  Fly    50 PDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSI 114
            |||||||:||||..:.........|:..|.|.|....|.......|||.::...:....||:|||
Zfish    14 PDGGWGWVVLLGGFVITGFSYAFPKAISVYFKELMHDFGCGYKDTAWISSIILAMLYGSGPISSI 78

  Fly   115 LSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLR 179
            :..|:..|.|.|:||..||||||.:.:|:||..|||:.||:.|:|..|:|.|::.::.:||.|.|
Zfish    79 MVNKFGCRPVMLVGGLLASLGMISASFATSIIHLYITAGVITGLGLALNFQPSLIMLGAYFDKRR 143

  Fly   180 GLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRA 244
            .|||||..:||.:....|.||.:.||:.||:.|..||.||:.||....
Zfish   144 PLANGLAAAGSPVFLSALSPLGQLLLDQYGWRGGFLITGGLLLNCCTC----------------- 191

  Fly   245 RQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAVV 309
                         |.||:
Zfish   192 -------------GAVMR----------------------------------------------- 196

  Fly   310 QSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRLS 374
                               |::|.:|...       :|.....:|......|.:...|:.|
Zfish   197 -------------------PLKLKERKAC-------NQELKEMLPPEAGQENIVCENNNDK---- 231

  Fly   375 KRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQAQ 439
                                                                             
Zfish   232 ----------------------------------------------------------------- 231

  Fly   440 QPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATDL 504
            ||.:.|..|.|:|:|...::.:|:.....:......|||.::.:.:|.....:|:|||::...|:
Zfish   232 QPSKKKLLDFSVLRDKGLIIYIIAKFIVVLGLFVPTILLVNYAKDQGVPDKEAAFLLSIIGFIDI 296

  Fly   505 IGRIGGSALSDMGYI-PKTWYFVG-GLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYVGITA 567
            ..|.....::.:.:: ||..||.. .|..:||:......:..|..:..:|..|||:.|:...:..
Zfish   297 FARPTCGVVAGLKWVRPKMSYFFSLALLFNGLTDVCSATSTDYKGLIIFCVFFGLSYGMVGALQF 361

  Fly   568 VIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGA---SLW 629
            .::..::||.:.:|:.|:.|....:..|:|||...|..:...:|..:|:..|..|:...   :|.
Zfish   362 EVLMGIVGTSKFSSALGLVLLFEAVAVLIGPPSAGYLVDKYKNYELIFYMAGGELITAGIFLALA 426

  Fly   630 SF--MPWINRRKANAEEQLDAQI 650
            ||  :....|:.:...:|.|.::
Zfish   427 SFCCISQKKRKDSPQTQQTDVEV 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	136/608 (22%)
		MFS	59..>234	CDD:119392	66/174 (38%)
		MFS	<449..633	CDD:119392	44/190 (23%)
slc16a8	NP_001311456.1	2A0111	14..441	CDD:331689	134/598 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.820