Protein Alignment hrm and slc16a12a

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: XP_009291327.1
• Gene: slc16a12a / 557762
• ZFINID: ZDB-GENE-080721-24
• Length: 617
• Species: Danio rerio
• Alignment Length: 675
• Identity: 150/675 - (22%)
• Similarity: 278/675 - (41%)
• Gaps: 135/675 - (20%)

  Fly     1 MHKEKIIN-----------SQNASKINQKDHKPNGNTNESRHKTVSLINKKDDKEYDLVP----- 49
            |.:::::|           ::...|..|:..:..|.....:...:.:..|.        |
Zfish     9 MREKELVNTSRTEPGRAKPAETGQKRKQEAERSEGMKERMKRGRLEMGEKN--------PCLATA 65

  Fly    50 PDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSI 114
            |||||||:::.|..||.:......:...:.|.||...|:...:..|||.:|.........|:.|.
Zfish    66 PDGGWGWMIVAGCFLTTVCTRAVTRCVSIFFVEFQLYFSRDYSATAWIHSLLDCTTMLCAPLGSY 130

  Fly   115 LSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLR 179
            :..:.|.|...::||..:|.|::||..|:|:||||::.|||.|:|..||:.|.:.:|.|||.:.:
Zfish   131 IGNRLSSRIAIMIGGLLSSTGLLLSSLATSVEFLYLTLGVLTGVGFALSYTPAIAMVGSYFRQRK 195

  Fly   180 GLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRA 244
            .||.|:.:|||.:|:.||.|.::.|:|.:.:.|:.||:.|:..::.|......|::..     |.
Zfish   196 ALAYGIAMSGSGIGTFILAPAVQLLIEFFSWRGALLILAGLVSHLCVCGALMRPLQSQ-----RG 255

  Fly   245 RQ---ALENIPEEEDIGIVMKF----------ENVDEPVPKNEPADKPLLPYN-----SPPSPLY 291
            ||   .|||....:.:.:.:.:          ..|.:.:.|.||::..|....     ......:
Zfish   256 RQNKMDLENGKTVDLLNVKLAYVELRGSMEVTHAVVKEMEKKEPSENMLRNGKGWIEADDMKQSH 320

  Fly   292 LPGDERLQFVRSASAAVVQSYSKSGDEFQSRSRKISTPV-----RLP-------QRNQTFTPGQL 344
            |.|:|......|.:...|..:|      :...|.||.|.     .||       |:|.||
Zfish   321 LDGEENHGQDLSENPKTVNKWS------EEEPRTISIPALVQSSGLPLENLLKYQKNITF----- 374

  Fly   345 NSQSSLYAVPEGRSSSNKLTLRNSSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLR 409
                     ||.:|..      |:::|.::|.....:..|..|.....|.|
Zfish   375 ---------PESKSEG------NNNQSTVAKSKVVKAKLLKESKENVWSVL-------------- 410

  Fly   410 SMGSSGTGHAGDSTGQDGSYADVDARGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYT-N 473
                                            :::...:.|.|..|.:|::|:|....|...: .
Zfish   411 --------------------------------RKTVLKEYSFLLIPDFLLLLVSFLFLAYGCSVP 443

  Fly   474 FIILLPSFGEARGFNKSLSAYLLSVVSATDLIGRIGGSALSDMGYIP--KTWYFVGGLSISGLSL 536
            |:.|:| :..:.|.:...:|.::|::..:.:||.|....::|...:.  :...::..:...|||.
Zfish   444 FVYLVP-YSLSAGVSPQQAALVMSILGVSGIIGTITFGWIADRKCLRPYRVVSYMLAVGSEGLSC 507

  Fly   537 ALLPFAWTYSSVCFWCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLC 601
            ..||....:|.:..:..::|...|.||.:..|:.:|.:.:.:|||:.|:..|::.:..|:.||:.
Zfish   508 LFLPLLSGFSLLVPFSLIYGYFDGAYVALIPVVTSDTVSSAQLTSALGVVYFLHAIPYLISPPIG 572

  Fly   602 NYWFEAVNDYNPLFHALGLTLLAGA 626
            .:..:....|...|...|::|:..|
Zfish   573 GWLVDQTGSYTATFILSGVSLICSA 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	144/616 (23%)
		MFS	59..>234	CDD:119392	56/174 (32%)
		MFS	<449..633	CDD:119392	42/181 (23%)
slc16a12a	XP_009291327.1	2A0113	55..601	CDD:273325	145/629 (23%)
		MFS	75..604	CDD:119392	136/601 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		otm25394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.020