Protein Alignment hrm and slc16a12

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_989310.1
• Gene: slc16a12 / 394932
• XenbaseID: XB-GENE-1012784
• Length: 473
• Species: Xenopus tropicalis
• Alignment Length: 621
• Identity: 137/621 - (22%)
• Similarity: 237/621 - (38%)
• Gaps: 190/621 - (30%)

  Fly    26 TNESR--HKTVSLINKKDDKEYDLVPPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFN 88
            |.|.|  ||               .||||||||::::|.....:......:...:.|.||...|.
 Frog     2 TQEKRNLHK---------------APPDGGWGWMIVIGCFFVTVCTRAVTRCISIFFVEFQSYFA 51

  Fly    89 SSPTKAAWIPALCYFLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYG 153
            ....:.|||.::.........|:.|.:|..:|.:...:|||..||.|::||.:|:|:|:||::.|
 Frog    52 QDYARTAWIHSIVDCSTMLCAPIGSYVSNHFSCQVGIILGGVLASTGLVLSSFATSLEYLYLTLG 116

  Fly   154 VLVGIGAGLSFPPTVYIVTSYFAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMG 218
            ||.|:|..|.:.|.:.:|..||.|.:.||.|:.:|||.:|:.||.|:::.|:|.:.:.|:.||:|
 Frog   117 VLTGLGFALCYSPAIAMVGKYFEKRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILG 181

  Fly   219 GITLNVFVAALFYEPV--EQHMVRVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLL 281
            |...|:.|......|:  ::..:..|..::.:||.|.:.
 Frog   182 GFVSNLCVCGALMRPITLKEDSLHYPLKQEQMENEPTQS-------------------------- 220

  Fly   282 PYNSPPSPLYLPGDERLQFVRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNS 346
                                                                        |:|:|
 Frog   221 ------------------------------------------------------------GRLDS 225

  Fly   347 QSSLYAVPEGRSSSNKLTLRNSSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSM 411
            ..|    |..:..|:|         ||          .|.:           .||:|
 Frog   226 SCS----PLCQDCSHK---------RL----------CYCT-----------KKEYS-------- 248

  Fly   412 GSSGTGHAGDSTGQDGSYADVDARGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYT-NFI 475
                                                  .||| |.::|:.:|....|...: .|:
 Frog   249 --------------------------------------FLLK-PKFMVLAVSFLFLAYGCSPPFV 274

  Fly   476 ILLPSFGEARGFNKSLSAYLLSVVSATDLIGRIGGSALSDMGYIPKTWY--FVGGLSISGLSLAL 538
            .|:| :....|.:...:|:|:|::...|::|.|....::|..::.|..|  ::..:.:.||....
 Frog   275 YLVP-YALNVGVSNQEAAFLMSILGIIDIVGNITFGWVTDTRFLKKHRYCCYLIAVGLDGLCCLF 338

  Fly   539 LPFAWTYSSVCFWCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNY 603
            ||....:..:..:..:||...|.||.:..|:..|::||..|:|:.|:..|::.:..||.||:..:
 Frog   339 LPILTRFQLLVPFSVMFGYFDGAYVALIPVVTGDVVGTSSLSSALGVVFFLHAVPYLVSPPIAGW 403

  Fly   604 WFEAVNDYNPLFHALGLTLLAGASLWSFMPWINRRK 639
            ..:...||...|...|.:::..|.|.:....|||.|
 Frog   404 LVDTTGDYTAAFLLSGFSMIFCAVLLALAKIINRIK 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	132/596 (22%)
		MFS	59..>234	CDD:119392	55/174 (32%)
		MFS	<449..633	CDD:119392	47/186 (25%)
slc16a12	NP_989310.1	2A0111	12..444	CDD:331689	132/596 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020