Protein Alignment hrm and slc16a1b

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_956379.1
• Gene: slc16a1b / 368274
• ZFINID: ZDB-GENE-030515-5
• Length: 461
• Species: Danio rerio
• Alignment Length: 618
• Identity: 131/618 - (21%)
• Similarity: 226/618 - (36%)
• Gaps: 207/618 - (33%)

  Fly    49 PPDGGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGP 110
            ||:|||||.|::|:.::   :...|   ||..|.|.|....||::.::.:||.::...:..:.||
Zfish    13 PPEGGWGWAVVVGAFISIGFSYAFP---KSITVFFKEIEVIFNATSSQVSWISSIMLAVMYAGGP 74

  Fly   111 VSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYF 175
            :||||..|:..|.:.:.||..:..|::.:.:..::|.||...||:.|:|...:..|.:.::..||
Zfish    75 ISSILVNKFGSRPIMIAGGCLSGTGLVAASFCDTVEGLYFCVGVIGGLGLAFNLNPALTMIGKYF 139

  Fly   176 AKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVR 240
            .|.|.:|||:.::||.:....|.||..||.:.:|:.||.||:||..||..||.....|:.
Zfish   140 YKRRPIANGIAMAGSPVFLSTLAPLNSWLFDQFGWRGSFLILGGALLNCCVAGSLMRPIG----- 199

  Fly   241 VPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSAS 305
                                          ||.:||               :|
Zfish   200 ------------------------------PKPQPA---------------IP------------ 207

  Fly   306 AAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSK 370
                    |...|.:            ||..:|
Zfish   208 --------KEDAEIK------------PQEKKT-------------------------------- 220

  Fly   371 SRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDAR 435
                           |....:|
Zfish   221 ---------------VMQTING------------------------------------------- 227

  Fly   436 GQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVS 500
                      |.||:|.....:|:.|:.|..........::.|.::.:::..:|..:|:|||:::
Zfish   228 ----------FLDLTLFTHRGFLLYLLGNVIMFFGLFAPLVFLSNYAKSKHISKDKAAFLLSILA 282

  Fly   501 ATDLIGRIGGSALSDMGYIPKT--------WYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGL 557
            .||:|.|      ..||.:..|        ::|...:..:|:...|.|.:..|.....:...||:
Zfish   283 FTDMIAR------PSMGLVANTRWVRPRIQYFFAASVLYNGVCHLLAPLSTDYLGFAIYAVFFGV 341

  Fly   558 ASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTL 622
            |.|....:....:.|::|.:|.:|:.|:...|.....|:||||.....:..:||...:...|:.|
Zfish   342 AFGWLSSVLFETLMDLVGAQRFSSAVGLVTIVECAPVLLGPPLLGRLNDIYDDYKYTYQGCGIVL 406

  Fly   623 LAGASLWSFMPW-INRR---KANAEEQLDAQIE 651
            :. ||::.|:.. ||.|   |...||:..|::|
Zfish   407 VI-ASIFLFVGMGINYRLVDKEKKEEEKRAKLE 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	131/618 (21%)
		MFS	59..>234	CDD:119392	55/177 (31%)
		MFS	<449..633	CDD:119392	45/191 (24%)
slc16a1b	NP_956379.1	2A0113	1..442	CDD:273325	131/618 (21%)
		MFS	20..415	CDD:119392	116/586 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.820