Protein Alignment hrm and out

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_573378.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 678
• Identity: 152/678 - (22%)
• Similarity: 257/678 - (37%)
• Gaps: 106/678 - (15%)

  Fly    13 SKINQKDHKP--NGNTNESRHKTVSLINKKDDKEYDLVPPDGGWGWLVLLGSCLTNILIPGTIKS 75
            |.:.:|:|..  |..|...:.|.    ..|.|...|.|.|||||||:|.|.:.|.|..:...::.
  Fly     4 SSLTEKNHTQVYNDTTKPKKPKR----RDKSDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQ 64

  Fly    76 FGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSF 140
            :|:::.....:......:...|..:...:.|.:|.|:..:..::::|.|.|.|.:.|.||:.||.
  Fly    65 YGLIYRVRMQSLGFDAKQTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSA 129

  Fly   141 WASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLRGLANGLCISGSALGSIILPPLLRWLL 205
            :.::.....|....:.|||.||:...|...|.:||...|..|.|...:.:.||.|..|.:...||
  Fly   130 FCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLL 194

  Fly   206 ETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPR--ARQALENIPEEEDIGIVMKFENVDE 268
            ..||..|:.||..||.:|..:.||..:||..| |:.|.  ....:|.|.|.|.:...:...|.:.
  Fly   195 GYYGAQGTILIYAGIAMNAILCALTLQPVLWH-VKKPEKPVHNTIEGIAETEKLQPELLEANGNL 258

  Fly   269 PVPKNEP--------------------ADKPLLPYNSPPSPLY---LPGDERLQFVRS---ASAA 307
            ..|.|:|                    :.:.|...:.|..|.|   .||...|.....   .|..
  Fly   259 LSPSNDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPERPGYEITEPGTPMLARANDGWFGSKL 323

  Fly   308 VVQSYSKSGDEFQSRS---RKISTPVR----------------LPQRNQTFTPGQLN-------- 345
            .:.|.|..|...::|.   |::|:..|                .|.....:.|...|
  Fly   324 SLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQNRHDQGPDTPSAAALYKPNYFNREREDLDR 388

  Fly   346 --SQSSLYAVPEGRSSSNKLTLRNSSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSL 408
              |::|:|:.| |:....:.|.. ..|:.|.|.:.|....|:
  Fly   389 YASKTSVYSRP-GQDELLRCTCA-EDKALLQKTAESLQVNLF----------------------- 428

  Fly   409 RSMGSSGTGHAGDSTGQDGSYADVDARGQAQQPQR-SKFFDLSLLKDPMYLVILISNSTNAISYT 472
                         :...|.:.|:.:|:.:....|: ||||||.||:|..::.:.:..|.......
  Fly   429 -------------NNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEM 480

  Fly   473 NFIILLPSFGEARGFNKSLSAYLLSVVSATDLIGRIGGSALSDMGYIPKTWYFVGGLSISGLSLA 537
            ||.:|.|....:.|:..:..:.::|:::..|:..|.......:...:.....|..|:....:...
  Fly   481 NFSVLTPFILNSFGYTDTQISLVMSLLACMDISVRFLAPLALEKVKLDNRVLFAFGILCIAVGRV 545

  Fly   538 LLPFAWTYSSVCFWCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCN 602
            ::.|..:|..:.....|.|.........:.:|:...:...||.::.|:.|..|.:......|:..
  Fly   546 VVAFTDSYEIMIGVFLLIGFGKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNTIFSFAMGPILG 610

  Fly   603 YWFEAVNDYNPLFHAL-GLTLLAGASLW 629
            ...||.. |....|.: .||||| ..||
  Fly   611 ILTEAYG-YAATIHTINALTLLA-LLLW 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	49/175 (28%)
		MFS	<451..633	CDD:475125	36/180 (20%)
out	NP_573378.1	MFS	44..>221	CDD:475125	49/176 (28%)
		MFS	<459..626	CDD:475125	29/167 (17%)