Protein Alignment hrm and Slc16a12

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001178566.1
• Gene: Slc16a12 / 309525
• RGDID: 1311468
• Length: 486
• Species: Rattus norvegicus
• Alignment Length: 593
• Identity: 131/593 - (22%)
• Similarity: 224/593 - (37%)
• Gaps: 169/593 - (28%)

  Fly    49 PPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSS 113
            ||||||||:::.|..|..|......:...:.|.||...|....::.|||.::...:.....|:.|
  Rat    12 PPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGS 76

  Fly   114 ILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKL 178
            ::|.:.|.:...:|||..||.|:||..:|:|::.||:|.|||.|:|..|.:.|.:.:|..||::.
  Rat    77 VVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRR 141

  Fly   179 RGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPR 243
            :..|.|:.:|||.:|:.||.|:::.|:|.:.:.|:.||:||..||:.|......|
  Rat   142 KAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRP---------- 196

  Fly   244 ARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAV 308
                   |..:||                             |..|
  Rat   197 -------ITLKED-----------------------------PSGP------------------- 206

  Fly   309 VQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRL 373
                .||.|             |..||...       .|:|.|
  Rat   207 ----EKSHD-------------RDAQREDC-------KQASPY---------------------- 225

  Fly   374 SKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQA 438
               ||.|                   ||::......|:             |.|
  Rat   226 ---SPLT-------------------KEWTETRLCCSL-------------QQG----------- 244

  Fly   439 QQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATD 503
                    :...|:.|  ::|:.:|....|...:...:.|..:..:.|.:...:|:|:|::...|
  Rat   245 --------YGFLLMSD--FVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVID 299

  Fly   504 LIGRIGGSALSDMGYIPKTWY--FVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYVGIT 566
            ::|.|....|:|...:....|  ::..:::.||....||...::..:..:...||...|.||.:.
  Rat   300 IVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLI 364

  Fly   567 AVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASLWSF 631
            .|:.|:::||..|:|:.|:..|::.:..||.||:..:..:....|...|...|..::..:.|..|
  Rat   365 PVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGF 429

  Fly   632 MPWINRRK 639
            .....|.|
  Rat   430 AKIAKRMK 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	131/593 (22%)
		MFS	59..>234	CDD:119392	56/174 (32%)
		MFS	<449..633	CDD:119392	42/185 (23%)
Slc16a12	NP_001178566.1	2A0111	12..451	CDD:331689	131/593 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..221		10/91 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920