Protein Alignment hrm and Slc16a7

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_058998.2
• Gene: Slc16a7 / 29735
• RGDID: 3691
• Length: 489
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 141/613 - (23%)
• Similarity: 229/613 - (37%)
• Gaps: 185/613 - (30%)

  Fly    48 VPPDGGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLG 109
            :||||||||:|:..|.::   :...|   |:..|.|::..|.|.::.::.|||.::...:..:.|
  Rat    18 LPPDGGWGWVVVCASFISIGFSYAFP---KAVTVFFNDIKDIFKTTSSQIAWISSIMLAVMYAGG 79

  Fly   110 PVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSY 174
            |:||:|...|..|.|.::||.....||||:.::||:..||::.|.:.|:|...:..|.:.|:..|
  Rat    80 PISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLGLAFNLQPALTIIGKY 144

  Fly   175 FAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMV 239
            |.:.|.||||..::||.:....|.|..::|..:||:.||.||:|.|.|:..||.....||
  Rat   145 FYRKRPLANGFAMAGSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAGCLMRPV----- 204

  Fly   240 RVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSA 304
                                                          .|||            |:|
  Rat   205 ----------------------------------------------GPSP------------RAA 211

  Fly   305 SAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSS 369
                 :|.||.|..                                               ::||
  Rat   212 -----KSKSKVGSR-----------------------------------------------QDSS 224

  Fly   370 KSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDA 434
            ..||||          |||
  Rat   225 TKRLSK----------VST---------------------------------------------- 233

  Fly   435 RGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVV 499
               |::..|  |.|..|.....:|:.|..|....:.....||.|..:.:.:|.:...||:||||:
  Rat   234 ---AEKINR--FLDFGLFTHRGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGVDDYNSAFLLSVM 293

  Fly   500 SATDLIGRIGGSALSDMGYI-PKTWY-FVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGIY 562
            :.||:..|.....:::...| |:..| |...:..:|:...|.|.|.:|:::..:...||:..|..
  Rat   294 AFTDMFARPSVGLIANTSLIRPRIQYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSI 358

  Fly   563 VGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGAS 627
            ..:....:.|.:|..|.:|:.|:...|.....|.||||.....:....|..|:.|.|:.:|:...
  Rat   359 SSLLFECLMDQVGASRFSSAVGLVTIVECCPVLFGPPLAGKLLDITGQYKYLYIASGIVVLSSGI 423

  Fly   628 LWSFMPWINRRKANAEEQLD-AQIEKAA 654
            .......||.|....|.:.: |:.:|:|
  Rat   424 YLLICNAINYRLLEKERKREKARRKKSA 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	59/178 (33%)
		MFS	<451..633	CDD:475125	45/183 (25%)
Slc16a7	NP_058998.2	2A0113	21..436	CDD:273325	135/593 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..227		11/84 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	441..489		3/11 (27%)