Protein Alignment hrm and Slc16a11

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: XP_038941393.1
• Gene: Slc16a11 / 287450
• RGDID: 1311125
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 119/595 - (20%)
• Similarity: 208/595 - (34%)
• Gaps: 209/595 - (35%)

  Fly    49 PPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSS 113
            ||||||||:|...:...|.|..|.::|.|:...:..:.|..|....||:.||...:..:..||.|
  Rat   154 PPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGS 218

  Fly   114 ILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKL 178
            .||.::..|.|.::||...|||::.|.:|.|:..||:..|:|.|.|..|.|.|.:..::.||::.
  Rat   219 ALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRR 283

  Fly   179 RGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPR 243
            |.||.||.::|:...|::|.|.|::||:|:|:.|:.|::|.:||:
  Rat   284 RVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLH-------------------- 328

  Fly   244 ARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAV 308
                                                |.|..:...||.|.||
  Rat   329 ------------------------------------LTPCGALLRPLALSGD------------- 344

  Fly   309 VQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRL 373
                                |:..|:
  Rat   345 --------------------PLAPPR--------------------------------------- 350

  Fly   374 SKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQA 438
                          ||                  |.::|
  Rat   351 --------------TP------------------LAALG-------------------------- 357

  Fly   439 QQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATD 503
                      |.|.:.|.:.|..:..:.....|....:.|......:|.....:|.:::|.:..|
  Rat   358 ----------LGLFRRPAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGD 412

  Fly   504 LIGRIGGSALSDMGYIPKTWYFVGGLSISG---LSLALLPFAWTYSSVCFWCA-------LFGLA 558
            ...|:....|:|.|::|.....|...|::|   |::.|:|...|...   |.|       .:||:
  Rat   413 ASARLVSGWLADQGWVPLPRLLVVFGSLTGLGVLAVGLVPTVGTEEG---WGAPLLAAAGAYGLS 474

  Fly   559 SGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLL 623
            :|.|..:...::..::|...:..:.|:.:.:..|..|:||||..:..:...|::..|......:|
  Rat   475 AGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFIL 539

  Fly   624 AGASLWSFMP 633
            :|:.::..:|
  Rat   540 SGSFIYMGLP 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	59/175 (34%)
		MFS	<451..633	CDD:475125	39/191 (20%)
Slc16a11	XP_038941393.1	PHA03378	<42..158	CDD:223065	3/3 (100%)
		MFS_MCT11_13	160..549	CDD:340981	112/587 (19%)