Protein Alignment hrm and SLC16A9

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: XP_016871372.1
• Gene: SLC16A9 / 220963
• HGNCID: 23520
• Length: 551
• Species: Homo sapiens
• Alignment Length: 624
• Identity: 156/624 - (25%)
• Similarity: 254/624 - (40%)
• Gaps: 162/624 - (25%)

  Fly    50 PDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSI 114
            |||||||:::..|.||..|..|:..:.|||:.|:.|||.....|.||:.:|...:.....||.|:
Human     7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSL 71

  Fly   115 LSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLR 179
            ....:..|.||:..|...:.|::||.:|.:|.||:.|||::||:|.||.:..||.|...||...|
Human    72 CVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDDRR 136

  Fly   180 GLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRA 244
            |||.||..:||::|..|...|.|.|:|.||..|..||:|.:.||:........|::.....:|:
Human   137 GLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMRPLQSSDCPLPK- 200

  Fly   245 RQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAVV 309
            :.|.|::|::..| ...|.:|::|.:   ...||   .|:|         :|:.:...:
Human   201 KIAPEDLPDKYSI-YNEKGKNLEENI---NILDK---SYSS---------EEKCRITLA------ 243

  Fly   310 QSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRLS 374
                 :||..|.         .|..:|.|.|           ...|..:...|:..:.....:|:
Human   244 -----NGDWKQD---------SLLHKNPTVT-----------HTKEPETYKKKVAEQTYFCKQLA 283

  Fly   375 KRSPSTSSFLYVSTPYHGSTLS-FQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQA 438
            ||...    ||.:  |.|.|:: |:.|.||:
Human   284 KRKWQ----LYKN--YCGETVALFKNKVFSA---------------------------------- 308

  Fly   439 QQPQRSKFFDLSLLKD-----PMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSV 498
                   .|...||.|     |..|:..::.|:| :....||  :|               |:|:
Human   309 -------LFIAILLFDIGGFPPSLLMEDVARSSN-VKEEEFI--MP---------------LISI 348

  Fly   499 VSATDLIGRIGGSALSDMGYIPKTWYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYV 563
            :.....:|::....|:|..:|...:.:|..|.|.||:|..:|||.:|.::.....:.|..:|.:
Human   349 IGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW- 412

  Fly   564 GITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPL--------------------------CN 602
            .|...:....:|.|:|..:|||.:|..||...:|||:                          ||
Human   413 SIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGKIFILKSSHFTVLPCHISRYRGPDCN 477

  Fly   603 ----------------YWFEAVNDYNPLFHALGLTLLAG 625
                            ::::....|:..|:..|..:|.|
Human   478 SSTDLYKRNLHGTSHGWFYDWTQTYDIAFYFSGFCVLLG 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	156/624 (25%)
		MFS	59..>234	CDD:119392	65/174 (37%)
		MFS	<449..633	CDD:119392	48/224 (21%)
SLC16A9	XP_016871372.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1	Normalized mean entropy	S4908
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.770