Protein Alignment hrm and Slc16a5

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001074403.1
• Gene: Slc16a5 / 217316
• MGIID: 2443515
• Length: 468
• Species: Mus musculus
• Alignment Length: 606
• Identity: 136/606 - (22%)
• Similarity: 225/606 - (37%)
• Gaps: 181/606 - (29%)

  Fly    51 DGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSIL 115
            ||.|.|:|||.|.:|..|..|.....||.|::....|.:|.::.:|.|::...:....||:.|||
Mouse     9 DGRWAWVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNSETSWFPSILGAMVHGGGPLCSIL 73

  Fly   116 SVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLRG 180
            ...:..|...:|||..|||||::|.::.|:..|:::.||:.|:|...||..::.:|..||.:.|.
Mouse    74 VKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLGMCFSFQSSITVVGLYFVRRRP 138

  Fly   181 LANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRAR 245
            |||.|...|.::|..:.|.|.|:||||.|:.|:.||.|||.|:..|......||
Mouse   139 LANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLRPV----------- 192

  Fly   246 QALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAVVQ 310
             |...:|                     ||.:.||||...|              .||..|..|.
Mouse   193 -ATNEVP---------------------EPKEDPLLPPKIP--------------TRSCLATCVS 221

  Fly   311 S--YSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRL 373
            :  |..:.|              :.:.|..|         .:|.        ..:|..|     |
Mouse   222 TIRYHLAFD--------------ILRHNMGF---------CIYV--------TGVTWMN-----L 250

  Fly   374 SKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQA 438
            ....|..  ||.....:||
Mouse   251 GFALPHI--FLVPYAMHHG---------------------------------------------- 267

  Fly   439 QQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATD 503
                          .|..:..:|:|    .:.:.| |.|.|..|......|||:||
Mouse   268 --------------VDDYWAAMLMS----IVGFCN-IFLRPMAGLLLAGRKSLAAY--------- 304

  Fly   504 LIGRIGGSALSDMGYIPKTWYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGLA-SGIYVGITA 567
                             :.:.|...:.|:||:..:...:..:..:..:|.::.|: .|:.:.:..
Mouse   305 -----------------RKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGVGILVFQ 352

  Fly   568 VIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASLWSFM 632
            |:| |::..:|..|:.|:...:.|:..|:.|||.....:..|:::.:|:.....|::| ||...:
Mouse   353 VLM-DIVPMDRFPSALGLFTILCGVTSLISPPLAGLLLDKTNNFSYVFYMSSGFLVSG-SLILGV 415

  Fly   633 PWINRRKANAEEQLDAQIEKA 653
            .:....|...::...|::|.|
Mouse   416 GFYAAEKKKLKQDGQAKMENA 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	64/175 (37%)
		MFS	<451..633	CDD:475125	37/182 (20%)
Slc16a5	NP_001074403.1	2A0113	8..461	CDD:273325	136/606 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	429..468		3/8 (38%)