Protein Alignment hrm and Slc16a5

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_001074403.1
• Gene: Slc16a5 / 217316
• MGIID: 2443515
• Length: 468
• Species: Mus musculus
• Alignment Length: 606
• Identity: 136/606 - (22%)
• Similarity: 225/606 - (37%)
• Gaps: 181/606 - (29%)

  Fly    51 DGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSIL 115
            ||.|.|:|||.|.:|..|..|.....||.|::....|.:|.::.:|.|::...:....||:.|||
Mouse     9 DGRWAWVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNSETSWFPSILGAMVHGGGPLCSIL 73

  Fly   116 SVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLRG 180
            ...:..|...:|||..|||||::|.::.|:..|:::.||:.|:|...||..::.:|..||.:.|.
Mouse    74 VKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLGMCFSFQSSITVVGLYFVRRRP 138

  Fly   181 LANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRAR 245
            |||.|...|.::|..:.|.|.|:||||.|:.|:.||.|||.|:..|......||
Mouse   139 LANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLRPV----------- 192

  Fly   246 QALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAVVQ 310
             |...:|                     ||.:.||||...|              .||..|..|.
Mouse   193 -ATNEVP---------------------EPKEDPLLPPKIP--------------TRSCLATCVS 221

  Fly   311 S--YSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRL 373
            :  |..:.|              :.:.|..|         .:|.        ..:|..|     |
Mouse   222 TIRYHLAFD--------------ILRHNMGF---------CIYV--------TGVTWMN-----L 250

  Fly   374 SKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQA 438
            ....|..  ||.....:||
Mouse   251 GFALPHI--FLVPYAMHHG---------------------------------------------- 267

  Fly   439 QQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATD 503
                          .|..:..:|:|    .:.:.| |.|.|..|......|||:||
Mouse   268 --------------VDDYWAAMLMS----IVGFCN-IFLRPMAGLLLAGRKSLAAY--------- 304

  Fly   504 LIGRIGGSALSDMGYIPKTWYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGLA-SGIYVGITA 567
                             :.:.|...:.|:||:..:...:..:..:..:|.::.|: .|:.:.:..
Mouse   305 -----------------RKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGVGILVFQ 352

  Fly   568 VIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASLWSFM 632
            |:| |::..:|..|:.|:...:.|:..|:.|||.....:..|:::.:|:.....|::| ||...:
Mouse   353 VLM-DIVPMDRFPSALGLFTILCGVTSLISPPLAGLLLDKTNNFSYVFYMSSGFLVSG-SLILGV 415

  Fly   633 PWINRRKANAEEQLDAQIEKA 653
            .:....|...::...|::|.|
Mouse   416 GFYAAEKKKLKQDGQAKMENA 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	135/604 (22%)
		MFS	59..>234	CDD:119392	62/174 (36%)
		MFS	<449..633	CDD:119392	37/184 (20%)
Slc16a5	NP_001074403.1	2A0113	8..461	CDD:273325	136/606 (22%)
		MFS	32..413	CDD:119392	121/558 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	429..468		3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920