Protein Alignment hrm and Slc16a11

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_694721.2
• Gene: Slc16a11 / 216867
• MGIID: 2663709
• Length: 447
• Species: Mus musculus
• Alignment Length: 595
• Identity: 123/595 - (20%)
• Similarity: 213/595 - (35%)
• Gaps: 209/595 - (35%)

  Fly    49 PPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSS 113
            ||||||||:|...:...|.|..|.::|.|:...:..:.|..|....||:.||...:..:..||.|
Mouse     8 PPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGS 72

  Fly   114 ILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKL 178
            .||.::..|.|.::||...|||::.|.:|.|:..||:..|:|.|.|..|.|.|.:..::.||::.
Mouse    73 ALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRR 137

  Fly   179 RGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPR 243
            |.||.||.::|:...|::|.|.|::||:|:|:.|:.|::|.:||:
Mouse   138 RVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLH-------------------- 182

  Fly   244 ARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAV 308
                                                |.|..:...||.|.||
Mouse   183 ------------------------------------LTPCGALLRPLALSGD------------- 198

  Fly   309 VQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRL 373
                                |:..|:     ||        |.|:..|
Mouse   199 --------------------PLAPPR-----TP--------LAALGLG----------------- 213

  Fly   374 SKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQA 438
                                  .|:.:.|       |:.:.||...|..
Mouse   214 ----------------------LFKRRAF-------SVFALGTALIGGG---------------- 233

  Fly   439 QQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATD 503
                              |.|..:....:|:.              :|.....:|.:::|.:..|
Mouse   234 ------------------YFVPYVHLGPHALD--------------QGMGGYGAALVVAVAAVGD 266

  Fly   504 LIGRIGGSALSDMGYIPKTWYFVGGLSISG---LSLALLPFAWTYSSVCFWCA-------LFGLA 558
            ...|:....|:|.|::|.....|...|::|   |::.|:|...|...   |.|       .:||:
Mouse   267 ACARLASGWLADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEG---WGAPLLAAAGAYGLS 328

  Fly   559 SGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLL 623
            :|.|..:...::..::|...:..:.|:.:.:..|..|:||||..:..:...|::..|......:|
Mouse   329 AGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFIL 393

  Fly   624 AGASLWSFMP 633
            :|:.::..:|
Mouse   394 SGSFIYMGLP 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	59/175 (34%)
		MFS	<451..633	CDD:475125	37/191 (19%)
Slc16a11	NP_694721.2	MFS	14..403	CDD:475125	116/587 (20%)