Protein Alignment hrm and Slc16a7

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_035521.1
• Gene: Slc16a7 / 20503
• MGIID: 1330284
• Length: 484
• Species: Mus musculus
• Alignment Length: 616
• Identity: 142/616 - (23%)
• Similarity: 231/616 - (37%)
• Gaps: 191/616 - (31%)

  Fly    48 VPPDGGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLG 109
            :||||||||:|:..|.::   :...|   |:..|.|.:..:.||::.::.|||.::...:..:.|
Mouse    13 LPPDGGWGWVVVCASFISIGFSYAFP---KAVTVFFKDIQEIFNTTSSQIAWISSIMLAVMYAGG 74

  Fly   110 PVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSY 174
            |:||:|...|..|.|.::||....:||||:.:::|:..||::.|.:.|:|...:..|.:.|:..|
Mouse    75 PISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLGLAFNLQPALTIIGKY 139

  Fly   175 FAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMV 239
            |.:.|.||||..::||.:....|.|..::|...||:.||.||:|||.|:..||.....||
Mouse   140 FYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPV----- 199

  Fly   240 RVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSA 304
                                                          .|||
Mouse   200 ----------------------------------------------GPSP--------------- 203

  Fly   305 SAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSS 369
                                                    |::                    .|
Mouse   204 ----------------------------------------NTK--------------------KS 208

  Fly   370 KSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDA 434
            ||::..|              |.|||....|.                    ||.|
Mouse   209 KSKVGSR--------------HDSTLKKASKV--------------------STAQ--------- 230

  Fly   435 RGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNF---IILLPSFGEARGFNKSLSAYLL 496
                   :.::|.|.||.....:|:.|   |.|.|.:...   ||.|..:.:..|.:...||:||
Mouse   231 -------KVNRFLDFSLFMHRGFLIYL---SGNVILFLGIFAPIIFLAQYAKHIGVDDYNSAFLL 285

  Fly   497 SVVSATDLIGRIGGSALSDMGYI-PKTWY-FVGGLSISGLSLALLPFAWTYSSVCFWCALFGLAS 559
            ||::..|:..|.....:::...| |:..| |...:..:|:...|.|.|.|||::..:...|||..
Mouse   286 SVMAFIDMFARPSVGLIANTSLIRPRIQYLFSSAIIFTGICHLLCPLATTYSALVVYVVFFGLGF 350

  Fly   560 GIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLA 624
            |....:....:.|::|..|.:|:.|::..|.....|.||||.....:...:|..|:.|.|..:|.
Mouse   351 GSISSLLFECLMDIVGATRFSSAVGLTTIVECCPVLFGPPLAGKLLDITGEYKYLYIASGTVVLV 415

  Fly   625 GASLWSFMPWINRRKANAEEQLD-AQIEKAA 654
            ..:.......||.|..:.|.:.: |:.:|:|
Mouse   416 SGTYLLIGNAINYRLLDKERKREKAKKKKSA 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	59/178 (33%)
		MFS	<451..633	CDD:475125	49/186 (26%)
Slc16a7	NP_035521.1	2A0113	5..431	CDD:273325	138/599 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	438..484		3/9 (33%)