Protein Alignment hrm and Slc16a2

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_033223.2
• Gene: Slc16a2 / 20502
• MGIID: 1203732
• Length: 545
• Species: Mus musculus
• Alignment Length: 612
• Identity: 120/612 - (19%)
• Similarity: 213/612 - (34%)
• Gaps: 197/612 - (32%)

  Fly    49 PPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFS----EFTDAFNSSPTKAAWIPALCYFLYSSLG 109
            ||:||:||:|:..:...|..|.|...|.|:|:|    |..:.......:|||:.||...:.....
Mouse   100 PPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCS 164

  Fly   110 PVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSY 174
            |:.||.:.:...|.....|.|.|.:|:..|.:.||:...|.:||:|.|.|...:|.|::.|:..|
Mouse   165 PIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHY 229

  Fly   175 FAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMV 239
            |.:..|||||:..:||::.|:..|.|::.|
Mouse   230 FQRRLGLANGVVSAGSSIFSMSFPFLIKML----------------------------------- 259

  Fly   240 RVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSA 304
                                                                             
Mouse   260 ----------------------------------------------------------------- 259

  Fly   305 SAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSS 369
                       ||:           ::|.|..|..
Mouse   260 -----------GDK-----------IKLAQTFQVL------------------------------ 272

  Fly   370 KSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDA 434
                       |:|::|.|..   :|:::|...||.               |:..:.|::    .
Mouse   273 -----------STFMFVLTLL---SLTYRPLLPSSQ---------------DTPSKRGAH----T 304

  Fly   435 RGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSV- 498
            ..|....|..|:|::.:.:...|.:.....:..|:.|....:.|..:.|.: |.:....::|.|
Mouse   305 LRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDK-FKEIKETWVLLVC 368

  Fly   499 VSATDLIGRIGGSALSDMGYIP---KTWYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASG 560
            :.||..:||:....:||.  ||   |.:..|....:.||...::|....:..:...|...||..|
Mouse   369 IGATSGLGRLVSGHISDS--IPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDG 431

  Fly   561 IYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAG 625
            .::.|.|.|..:::|..:.:.:.|..|.:..|..:.|||:.........||:..|:..|:..:.|
Mouse   432 FFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIG 496

  Fly   626 ASLWSFMPWINRRKANAEEQLDAQIEK 652
            |.:..|:|.:::|... :||.|:..:|
Mouse   497 AVILFFVPLMHQRMFK-KEQRDSSKDK 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	120/612 (20%)
		MFS	59..>234	CDD:119392	46/178 (26%)
		MFS	<449..633	CDD:119392	42/187 (22%)
Slc16a2	NP_033223.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..98
		2 X 22 AA approximate tandem repeats	29..72
		2A0111	92..519	CDD:331689	119/607 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	514..545		4/9 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820