Protein Alignment hrm and Slc16a1

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_033222.1
• Gene: Slc16a1 / 20501
• MGIID: 106013
• Length: 493
• Species: Mus musculus
• Alignment Length: 627
• Identity: 145/627 - (23%)
• Similarity: 240/627 - (38%)
• Gaps: 195/627 - (31%)

  Fly    49 PPDGGWGWLVLLGSCLT---NILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGP 110
            ||||||||.||:|:.::   :...|   ||..|.|.|....|:::.::.:||.::...:..:.||
Mouse    13 PPDGGWGWAVLVGAFISIGFSYAFP---KSITVFFKEIEVIFSATTSEVSWISSIMLAVMYAGGP 74

  Fly   111 VSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYF 175
            :||||..||..|.|.:.||..:..|:|.:.:.::::.||:..||:.|:|...:..|.:.::..||
Mouse    75 ISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLGLAFNLNPALTMIGKYF 139

  Fly   176 AKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVR 240
            .|.|.|||||.::||.:....|.||.:...:.:.:.||.||:||:.||..||.....|:.
Mouse   140 YKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCVAGSLMRPIG----- 199

  Fly   241 VPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSAS 305
                       ||:      :|.|
Mouse   200 -----------PEQ------VKLE----------------------------------------- 206

  Fly   306 AAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSK 370
                                                 :|.|:.||...  |:|.:|...:..|.|
Mouse   207 -------------------------------------KLKSKESLQEA--GKSDANTDLIGGSPK 232

  Fly   371 SRLSKRSPSTSSFLYVSTPYHGSTLS-FQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDA 434
                                 |..|| ||
Mouse   233 ---------------------GEKLSVFQ------------------------------------ 240

  Fly   435 RGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVV 499
                   ..:||.||||.....:|:.|..|..........::.|.|:|:::.|:...||:|||::
Mouse   241 -------TINKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSIL 298

  Fly   500 SATDLIGRIGGSALSDMGYIPKT--------WYFVGGLSISGLSLALLPFAWTYSSVCFWCALFG 556
            :..|::.|      ..||....|        ::|...:..:|:...|.|.:.||...|.:..:||
Mouse   299 AFVDMVAR------PSMGLAANTKWIRPRIQYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVFG 357

  Fly   557 LASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLT 621
            .|.|....:....:.|::|.:|.:|:.|:...|.....|:||||.....:...||...:.|.|:.
Mouse   358 FAFGWLSSVLFETLMDLIGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVI 422

  Fly   622 L-LAGASLWSFMPWINRR------KANAEEQLDAQIEKAAVD 656
            | :||..|:..| .||.|      ||..:::.:.:.::|:.|
Mouse   423 LIIAGIYLFIGM-GINYRLLAKEQKAEEKQKREGKEDEASTD 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	59/178 (33%)
		MFS	<451..633	CDD:475125	48/190 (25%)
Slc16a1	NP_033222.1	2A0113	1..466	CDD:273325	145/627 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	447..493		3/17 (18%)