Protein Alignment hrm and SLC16A13

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_963860.1
• Gene: SLC16A13 / 201232
• HGNCID: 31037
• Length: 426
• Species: Homo sapiens
• Alignment Length: 588
• Identity: 139/588 - (23%)
• Similarity: 216/588 - (36%)
• Gaps: 205/588 - (34%)

  Fly    49 PPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSS 113
            ||||||||:|:|.:...:.|:.|.::||||.|.||..||.....:.:||.::...:.....||.|
Human     7 PPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPVGS 71

  Fly   114 ILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKL 178
            .||.|:..|.|.:.||..|:|||:|:.:|:|:..||:|.|:|.|.|..|:|.||:..::.||::.
Human    72 ALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLACLSCYFSRR 136

  Fly   179 RGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEP---VEQHMVR 240
            |.||.||.::|..|.|....|..:|||..|.:.||.|::..::|::........|   .|...|.
Human   137 RSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVG 201

  Fly   241 VPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSAS 305
            .|||:..                                .|.::.|             |:|
Human   202 GPRAQLT--------------------------------SLLHHGP-------------FLR--- 218

  Fly   306 AAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSK 370
                                                         |.|        .|||.|
Human   219 ---------------------------------------------YTV--------ALTLIN--- 227

  Fly   371 SRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDAR 435
                     |..|:    ||         ....:||.                       |:|
Human   228 ---------TGYFI----PY---------LHLVAHLQ-----------------------DLD-- 245

  Fly   436 GQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVS 500
                             .||                      ||            :|:|||||:
Human   246 -----------------WDP----------------------LP------------AAFLLSVVA 259

  Fly   501 ATDLIGRIGGSALSDMGYIPKTWYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYVGI 565
            .:||:||:....|.|....|.|...:...:::|:||||.|.|...:::......:|..||....:
Human   260 ISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPL 324

  Fly   566 TAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASLWS 630
            ...::.:::||.|:....|:...:..:..|:||||..|..:...:|...|...|..||:|:.:..
Human   325 AFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILL 389

  Fly   631 FMP 633
            .:|
Human   390 TLP 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	64/175 (37%)
		MFS	<451..633	CDD:475125	44/181 (24%)
SLC16A13	NP_963860.1	MFS_MCT11_13	13..392	CDD:340981	132/580 (23%)