Protein Alignment hrm and mct-6

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_510705.1
• Gene: mct-6 / 181724
• WormBaseID: WBGene00015676
• Length: 594
• Species: Caenorhabditis elegans
• Alignment Length: 645
• Identity: 176/645 - (27%)
• Similarity: 288/645 - (44%)
• Gaps: 121/645 - (18%)

  Fly    48 VPPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVS 112
            :||||||||:|:|||...::...|.:.|||||.....:.|::|.|.||.|.:|...|....||::
 Worm    16 LPPDGGWGWVVVLGSFFVHVFADGFVYSFGVLVETLMEEFHASNTMAALIISLLTGLTLGSGPLA 80

  Fly   113 SILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAK 177
            |.:..||..|..|:.|...|.:|..||::|:::..:.|:.||::|.|.||.:.|.:.|||.||..
 Worm    81 SAVCNKYGCRITTITGAGVAFVGCALSYFATAMWHIVITVGVIMGTGFGLMYCPAIVIVTMYFEN 145

  Fly   178 LRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALF-----------Y 231
            .|.||.|:.::|:.:|:::..|:..:.:..||:.           :||:|.||           :
 Worm   146 KRSLATGIAVAGAGVGTVLFAPINAFFINNYGWR-----------SVFLAFLFILVLCALCGATF 199

  Fly   232 EPVEQHMVRVPRARQALENIPEEEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDE 296
            .|:|  ...||         .|||::...:..|:|.:.....|..:|..|  .||||.|     |
 Worm   200 APLE--FALVP---------DEEEEVNDEVLDEDVKKTAANEEHGEKATL--LSPPSLL-----E 246

  Fly   297 RLQFVRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFTPGQ-----LNSQSSLYAVPEG 356
            |..   |.|:.|    .|:|::.:..|...:..|....|::..|.|:     ||.:...|.
 Worm   247 RSM---SQSSGV----QKAGEKIRPASSMGAVDVESQPRSRRGTVGERDSGYLNRKDVFYT---- 300

  Fly   357 RSSSNKLTLR-NSSKSRLSKRSPSTSSFLYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAG 420
            .|.||....| :..|.|      ||.|.       ||           .|.::.|:.:..||...
 Worm   301 GSISNVAEFREDPDKYR------STGSL-------HG-----------RHTTVGSIPAHSTGRLD 341

  Fly   421 D---STGQDGSYADV-----------DARGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISY 471
            |   .:.:|....|:           :..|:......|....|.||.:|.:|:..|||...::.:
 Worm   342 DVREGSEEDSKAMDISEKTNGTDNTDNVEGKNMFKTISNMLSLELLLEPTFLLFAISNLLTSVGF 406

  Fly   472 TNFIILLPSFGEARGFNKSLSAYLLSVVSATDLIGRIGGSALSDMGY-IP----------KTWYF 525
            .:.:..||......|......:.:||....::.:|||....::|... :|          :.|.:
 Worm   407 NSPLYFLPLHATKIGLEPIQGSKVLSAFGVSNTVGRIIFGVVADHKLPLPGGIGNDTARNRLWMY 471

  Fly   526 VGGLSISGLSL-------ALLPFAWTYSSVCFWCALFGLASGIYVGITAVIMADMLGTERLTSSY 583
            ...|:|.||..       ..:|.| |||      ||||.:...|:.:|:||:.|:||.::||:::
 Worm   472 NISLTICGLLTVFCYQFNGFIPLA-TYS------ALFGFSIASYICLTSVILVDLLGLDKLTNAF 529

  Fly   584 GISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASLWSFMPWINRRKANAE 643
            |:.|...|:..:.|||:..|..:...:|...|...|:.|||...:...:|:. ::||.|:
 Worm   530 GLLLLWQGVGTVFGPPVSGYLADMTGNYTLSFVFCGVNLLASGLMLFGIPFF-QKKAKAK 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	176/644 (27%)
		MFS	59..>234	CDD:119392	57/185 (31%)
		MFS	<449..633	CDD:119392	54/201 (27%)
mct-6	NP_510705.1	MFS_MCT_SLC16	23..579	CDD:340910	166/626 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820