Protein Alignment hrm and mct-3

DIOPT Version :9

• Sequence 1: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_510308.1
• Gene: mct-3 / 181497
• WormBaseID: WBGene00010834
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 666
• Identity: 150/666 - (22%)
• Similarity: 287/666 - (43%)
• Gaps: 112/666 - (16%)

  Fly    19 DHKPNGNTNESRHKTVSLINKKDDKEYDLVPPDGGWGWLVLLGSCLTNILIPGTIKSFG-VLFSE 82
            |:....:...:.|:....:.|:.:....:.|||||:||.::..|.|.|:::.|.|.:.| :|...
 Worm     3 DNNQQADEKAAAHQDPETVEKELEDAGFIAPPDGGYGWAIVAASFLLNMIVDGVIFTVGKILQPA 67

  Fly    83 FTDAFNSSPTKAAWIPAL---CYFLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFWASS 144
            :..:|..|...||...::   |||.   .||::|:|...:..|.|.|.|...|:||.:||..|.:
 Worm    68 WVHSFGISEASAAMTMSILSGCYFF---AGPIASVLCNVFGCRQVALAGSLIAALGFLLSISAPN 129

  Fly   145 IEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLRGLANGLCISGSALGSIILPPL--LRWLLET 207
            |..||:|:|::.|.|.|:.:.|.:.|::.||||.|.:|.|:.:.||.:|:.:...|  :.|....
 Worm   130 IYVLYVSFGLIAGAGFGMMYLPAIVIISQYFAKKRSVATGIAVCGSGIGTTVFALLNDVVWDFVG 194

  Fly   208 YGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRARQALENIPEEEDIGIVMKFENVDEPVPK 272
            ..:....:....:|::...|.:...|::....::.:..:.||:            :|...|.||
 Worm   195 GDWKQFLVYTAAVTISGLGACILLRPLKPSKDQIEKVAKVLED------------YEEHKEKVP- 246

  Fly   273 NEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQ 337
                :.|||                               ||....|.| |.::.|..:|...:.
 Worm   247 ----ESPLL-------------------------------SKHNTPFLS-SLELHTAGKLENGHH 275

  Fly   338 TFTPGQLNSQSSLYAVPEGRSSSNKLTLR-----NSSKSRLSKRSPSTSSFLYVSTPYHGSTLSF 397
            |   |.:  :|.:.||.:.....||..||     :.|.:.::.|| .|.:........|..:|.|
 Worm   276 T---GSI--KSIVDAVSKEIEDLNKPLLRKDIFYSGSTTNIAARS-RTGTMTREEAAEHQQSLRF 334

  Fly   398 Q-----PKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADV----DARGQAQQPQRSKFFDLSLLK 453
            :     |:::.|...|         :|||:       .||    :::.|..:....:..|..||.
 Worm   335 RGKVETPQQYLSKADL---------NAGDN-------GDVAIANESKIQEIKQALKQLVDKELLF 383

  Fly   454 DPMYLVILISNS-TNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATDLIGRIGGSALSDMG 517
            .|.:|::..|.: |....|..||.|.....:..|...:..::.:|::...:::.|||...|:|.
 Worm   384 SPSFLLLAFSGTLTLCCFYVPFIYLGNHLDKIEGLTTAEKSFTVSLIGVLNIVARIGCGILADR- 447

  Fly   518 YIPKTWYFVGGLSI-------SGLSLALLPFAWTYSSVCFWCALFGLASGIYVGITAVIMADMLG 575
              |:    |..|::       :||:...:|....|.....:|..|.:....:..:.::|:.:::|
 Worm   448 --PE----VSALAVNNFALIAAGLATMTVPLYTAYWQFLAFCVPFSIGVACFAALRSIIVVELIG 506

  Fly   576 TERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFHALGLTLLAGASLWSFMPWINRRKA 640
            .|:|::::||.|...|:..:||.||.....:...:::..|:.:|..:....::...:..:.:|:.
 Worm   507 LEKLSNAFGILLTFMGVGAVVGSPLAAAMKDYTGNFDTSFYVMGALMTISGAMCIPLGGLRKREL 571

  Fly   641 NAEEQLDAQIEKAAVD 656
            ...:..||   |.|::
 Worm   572 ARSDSSDA---KKAIE 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	145/631 (23%)
		MFS	59..>234	CDD:119392	52/180 (29%)
		MFS	<449..633	CDD:119392	40/191 (21%)
mct-3	NP_510308.1	MFS_MCT_SLC16	39..563	CDD:340910	137/604 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820