Protein Alignment hrm and LOC1280341

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: XP_061511715.1
• Gene: LOC1280341 / 1280341
• VectorBaseID: AGAMI1_002494
• Length: 703
• Species: Anopheles gambiae
• Alignment Length: 704
• Identity: 165/704 - (23%)
• Similarity: 297/704 - (42%)
• Gaps: 143/704 - (20%)

  Fly    50 PDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSI 114
            |||||||:|:....|.||:|...::|||::|.:.....:.|.|||:.|..|...:..:||..:..
Mosquito    24 PDGGWGWMVVFAYGLANIMIVPVLQSFGLIFRDTFREIDISATKASIIINLASAVGMALGLFNGP 88

  Fly   115 LSVKYSYRTVTLLGGASASLGMILSFWASSIEFLY--ISYGVLVGIGAGLSFPPTVYIVTSYFAK 177
            |..:|.:|.:.:.||...|.|::|:  :|::.|.:  |:|.::..:|.|.........:.:||.:
Mosquito    89 LLRRYGFRKLAVAGGFLFSAGLMLT--SSAVHFAHFIITYSIISSLGMGFCNSSFSLALNTYFVE 151

  Fly   178 LRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVP 242
            .|..|.|:.::.:.||.|:||.|:..||..||.....||:|.:..::...||..:||:.|.:..|
Mosquito   152 RRNKAAGIAMTITGLGPILLPQLVSLLLTLYGARYCLLIIGALATHIIAGALLLQPVKWHTLPAP 216

  Fly   243 R-----ARQALENIPEEEDIGIV-MKF---ENVDEPVPKNEPADKPLL----------------- 281
            .     .:.|:...|...::.|| ::|   :..||...::|..:|...
Mosquito   217 SPPPADQQDAMLPCPPLPEVKIVPIEFGADDGADEAKEEDEFLEKGSYIDHDLDAQSVYGFELTS 281

  Fly   282 ------PYNSPPSPLYLPGDERLQFVRSASAAVVQSYSKSGDEFQSRSRKISTPVRLPQRNQTFT 340
                  .::.||.. ::....|:|..:|...|..|..:     .::||.|:.:....|.|  .|.
Mosquito   282 QIRQRESFSQPPGG-FISAAPRIQRAKSEVLAPAQQCA-----LETRSLKVESSTARPLR--WFQ 338

  Fly   341 PGQLNS---QSSLYAVPEGRSSSNKLTLRNSSKSRLSKRSPST---SSFLYVS-TP-----YHGS 393
            .|...|   .||| .:.:.|:||  |||...::|: .:|.||.   ||::.|. :|     :.||
Mosquito   339 SGSAESVHLGSSL-TMWDDRNSS--LTLAEETQSQ-QQRRPSQRRFSSYINVRFSPLPKRWFEGS 399

  Fly   394 ----TLSFQPKEFSSHLSLRSMGSSGTGHA-GDSTGQ---------------------------- 425
                .|....|.|....:....||.|:|.| |...|:
Mosquito   400 ADTVNLGSSMKIFDERYAGPRRGSLGSGVALGGGGGKLPALSENQGLTDEATHLPTIVRQLENTK 464

  Fly   426 ----------------DGSYADVDARGQAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNF 474
                            ||.:|.|           ...|||:||:|.:||.:::..|....:..||
Mosquito   465 VTSPPNDRPAAGGGKTDGFFAKV-----------VHLFDLTLLQDKVYLNMMLGMSIAVFAEINF 518

  Fly   475 IILLPSFGEARGFNKSLSAYLLSVVSATDLIGRIGGSALSD-MGYIPKTWYFV--GGLSISGLSL 536
            .:|.|......|::....|.::|.::..||:.|.....:.| :...|:..|.:  ..|.::..|:
Mosquito   519 SLLTPFILGDLGYSTEQIASIMSTLALADLLFRFISPFVGDYLKLTPRIMYMIALAMLIVTRFSI 583

  Fly   537 ALLPFAWTYSSVCFWCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGL-LQLVGP-- 598
            .|   |.:|..:.......|:|.|:.....::::...:..:||.|:..|.:..||: |..:||
Mosquito   584 LL---ARSYDEMVLVAFGLGVAKGVRSVYMSLVIPSYIPLKRLPSASSIQMTTNGIVLMTIGPCV 645

  Fly   599 PLCNYWFEAVNDYNPLFHALGLTLLAGASLWSFMPW------INRRKANAEEQL 646
            .|...|..:        ::..:.|:.|.::.:.:.|      ::|.:..|::::
Mosquito   646 GLLRDWTGS--------YSKSIILINGFTIVTLLMWSAELIYVHRCQNRAKQKV 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	53/177 (30%)
		MFS	<451..633	CDD:475125	40/187 (21%)
LOC1280341	XP_061511715.1	None