Protein Alignment hrm and Slc16a6

DIOPT Version :10

• Sequence 1: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: XP_036012103.1
• Gene: Slc16a6 / 104681
• MGIID: 2144585
• Length: 559
• Species: Mus musculus
• Alignment Length: 680
• Identity: 129/680 - (18%)
• Similarity: 222/680 - (32%)
• Gaps: 263/680 - (38%)

  Fly    13 SKINQKDHKPNGNTNESRHKTVSLINKKDDKEYDLVPPDGGWGWLVLLGSCLTNILIPGTIKSFG 77
            |::.||:.|.....|                .|..| |||||||.|.:......:...|.|||||
Mouse    83 SRMTQKNSKLCARAN----------------VYTQV-PDGGWGWAVAVSFFFVEVFTYGIIKSFG 130

  Fly    78 VLFSEFTDAFNSSPTKAAWIPALCYFLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFWA 142
            |.|::..|:|:.|.:|.:||.::|.|                                 :|:|
Mouse   131 VFFNDLMDSFDESNSKISWIISICVF---------------------------------VLTF-- 160

  Fly   143 SSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLRGLANGLCISGSALGSIILPPLLRWLLET 207
                         .|:|...||.|||.|::.||.|.|.:...:..:|.........|.:..|.|.
Mouse   161 -------------TGLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEH 212

  Fly   208 YGYHGSCLIMGGITLNVFVAALFYEPV-------------------EQHMVRVPRARQALENIPE 253
            .|:..|.|.:|.:.||:.|......|:                   .|:|:...:.|.::::|
Mouse   213 IGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTLEPRREVQYMLENEKTRTSIDSI-- 275

  Fly   254 EEDIGIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQFVRSASAAVVQSYSKSGDE 318
              |.|:.:...      |||.|::..:                                     |
Mouse   276 --DSGVELTTS------PKNVPSEAKM-------------------------------------E 295

  Fly   319 FQSRSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRLSKRSPSTSSF 383
            .::|:.:..|.|..|:.:|...|
Mouse   296 QETRAEQQQTLVTAPKHSQMKAP------------------------------------------ 318

  Fly   384 LYVSTPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQAQQPQRSKFFD 448
                                                                          ..|
Mouse   319 --------------------------------------------------------------LLD 321

  Fly   449 LSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATDLIGRIGGSAL 513
            .|:||:..::...:......:.:....:.:...|.:.|.:...:|:|||.::..::.||||...:
Mouse   322 FSVLKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAGFV 386

  Fly   514 SDMGYIPKTWYFVGGLSISGLSLALLP---FAWTYSSVCFW----CALF-----GLASGIYVGIT 566
            .:...|.|.:       |..:.:.||.   ||:|:::. ||    |::|     |...|.::.:.
Mouse   387 LNREPIRKIY-------IELICVILLTASLFAFTFATE-FWGLMLCSVFFGSMVGTIGGTHIPML 443

  Fly   567 AVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLFH--ALGLTLLAGASLW 629
            |  ..|::|.|:::|:.|:.:|:..:..|.||||.....:....|:..|:  |.|: .||...|.
Mouse   444 A--EDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGM-CLAAVCLA 505

  Fly   630 SFMP---WINRRKANAEEQLDAQIEKAAVD 656
            ...|   .:.:...:.|.|.|.|..||..|
Mouse   506 LVRPCKKGLCQNSHSGENQTDRQRGKALQD 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	44/175 (25%)
		MFS	<451..633	CDD:475125	45/195 (23%)
Slc16a6	XP_036012103.1	MFS_MCT7	108..508	CDD:340980	109/609 (18%)